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dc.contributor.authorLassale, Camille-
dc.contributor.authorGunter, Marc J-
dc.contributor.authorRomaguera, Dora-
dc.contributor.authorPeelen, Linda M-
dc.contributor.authorVan der Schouw, Yvonne T-
dc.contributor.authorBeulens, Joline W J-
dc.contributor.authorFreisling, Heinz-
dc.contributor.authorMuller, David C-
dc.contributor.authorFerrari, Pietro-
dc.contributor.authorHuybrechts, Inge-
dc.contributor.authorFagherazzi, Guy-
dc.contributor.authorBoutron-Ruault, Marie-Christine-
dc.contributor.authorAffret, Aurélie-
dc.contributor.authorOvervad, Kim-
dc.contributor.authorDahm, Christina C-
dc.contributor.authorOlsen, Anja-
dc.contributor.authorRoswall, Nina-
dc.contributor.authorTsilidis, Konstantinos K-
dc.contributor.authorKatzke, Verena A-
dc.contributor.authorKühn, Tilman-
dc.contributor.authorBuijsse, Brian-
dc.contributor.authorQuirós, José-Ramón-
dc.contributor.authorSánchez-Cantalejo, Emilio-
dc.contributor.authorEtxezarreta, Nerea-
dc.contributor.authorHuerta, José María-
dc.contributor.authorBarricarte, Aurelio-
dc.contributor.authorBonet, Catalina-
dc.contributor.authorKhaw, Kay-Tee-
dc.contributor.authorKey, Timothy J-
dc.contributor.authorTrichopoulou, Antonia-
dc.contributor.authorBamia, Christina-
dc.contributor.authorLagiou, Pagona-
dc.contributor.authorPalli, Domenico-
dc.contributor.authorAgnoli, Claudia-
dc.contributor.authorTumino, Rosario-
dc.contributor.authorFasanelli, Francesca-
dc.contributor.authorPanico, Salvatore-
dc.contributor.authorBueno-de-Mesquita, H Bas-
dc.contributor.authorBoer, Jolanda M A-
dc.contributor.authorSonestedt, Emily-
dc.contributor.authorNilsson, Lena Maria-
dc.contributor.authorRenström, Frida-
dc.contributor.authorWeiderpass, Elisabete-
dc.contributor.authorSkeie, Guri-
dc.contributor.authorLund, Eiliv-
dc.contributor.authorMoons, Karel G M-
dc.contributor.authorRiboli, Elio-
dc.contributor.authorTzoulaki, Ioanna-
dc.identifier.citationLassale C, Gunter MJ, Romaguera D, Peelen LM, Van der Schouw YT, Beulens JW, et al. Diet Quality Scores and Prediction of All-Cause, Cardiovascular and Cancer Mortality in a Pan-European Cohort Study. PLoS ONE 2016; 11(7):e0159025es
dc.identifier.issn1932-6203 (Online)-
dc.descriptionJournal Article;es
dc.description.abstractScores of overall diet quality have received increasing attention in relation to disease aetiology; however, their value in risk prediction has been little examined. The objective was to assess and compare the association and predictive performance of 10 diet quality scores on 10-year risk of all-cause, CVD and cancer mortality in 451,256 healthy participants to the European Prospective Investigation into Cancer and Nutrition, followed-up for a median of 12.8y. All dietary scores studied showed significant inverse associations with all outcomes. The range of HRs (95% CI) in the top vs. lowest quartile of dietary scores in a composite model including non-invasive factors (age, sex, smoking, body mass index, education, physical activity and study centre) was 0.75 (0.72-0.79) to 0.88 (0.84-0.92) for all-cause, 0.76 (0.69-0.83) to 0.84 (0.76-0.92) for CVD and 0.78 (0.73-0.83) to 0.91 (0.85-0.97) for cancer mortality. Models with dietary scores alone showed low discrimination, but composite models also including age, sex and other non-invasive factors showed good discrimination and calibration, which varied little between different diet scores examined. Mean C-statistic of full models was 0.73, 0.80 and 0.71 for all-cause, CVD and cancer mortality. Dietary scores have poor predictive performance for 10-year mortality risk when used in isolation but display good predictive ability in combination with other non-invasive common risk
dc.description.sponsorshipFunding: The coordination of EPIC is financially supported by the European Commission (DGSANCO) and the International Agency for Research on Cancer. The national cohorts are supported by Danish Cancer Society (Denmark); Ligue Contre le Cancer, Institut Gustave Roussy, Mutuelle Générale de l’Education Nationale, Institut National de la Santé et de la Recherche Médicale (INSERM) (France); German Cancer Aid, German Cancer Research Center (DKFZ), Federal Ministry of Education and Research (BMBF), Deutsche Krebshilfe, Deutsches Krebsforschungszentrum and Federal Ministry of Education and Research (Germany); the Hellenic Health Foundation (Greece); Associazione Italiana per la Ricerca sul Cancro-AIRC-Italy and National Research Council (Italy); Dutch Ministry of Public Health, Welfare and Sports (VWS), Netherlands Cancer Registry (NKR), LK Research Funds, Dutch Prevention Funds, Dutch ZON (Zorg Onderzoek Nederland), World Cancer Research Fund (WCRF), Statistics Netherlands (The Netherlands); Health Research Fund (FIS), PI13/00061 to Granada, Regional Governments of Andalucía, Asturias, Basque Country, Murcia (no. 6236) and Navarra, ISCIII RETIC (RD06/0020) (Spain); Swedish Cancer Society, Swedish Research Council and County Councils of Skåne and Västerbotten (Sweden); Cancer Research UK (14136 to EPIC-Norfolk; C570/ A16491 and C8221/A19170 to EPIC-Oxford), Medical Research Council (1000143 to EPIC-Norfolk, MR/ M012190/1 to EPIC-Oxford) (United Kingdom).es
dc.publisherPublic Library of Sciencees
dc.relation.ispartofPloS Onees
dc.subjectSistema cardiovasculares
dc.subjectEstudios de cohorteses
dc.subjectHábitos alimenticioses
dc.subjectEstado Nutricionales
dc.subjectEstudios Prospectivoses
dc.subjectFactores de Riesgoes
dc.subjectHábito de Fumares
dc.subjectÍndice de masa corporales
dc.subjectActividad motoraes
dc.subject.meshMedical Subject Headings::Anatomy::Cardiovascular Systemes
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studieses
dc.subject.meshMedical Subject Headings::Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Dietes
dc.subject.meshMedical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Feeding Behavior::Food Habitses
dc.subject.meshMedical Subject Headings::Diseases::Neoplasmses
dc.subject.meshMedical Subject Headings::Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Nutritional Statuses
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal Studies::Prospective Studieses
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factorses
dc.subject.meshMedical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Habits::Smokinges
dc.subject.meshMedical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Mass Indexes
dc.subject.meshMedical Subject Headings::Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Musculoskeletal Physiological Processes::Movement::Motor Activityes
dc.titleDiet Quality Scores and Prediction of All-Cause, Cardiovascular and Cancer Mortality in a Pan-European Cohort
dc.rights.accessRightsAcceso abiertoes
dc.contributor.authoraffiliation[Lassale,C; Gunter,MJ; Romaguera,D; Tsilidis,KK; Riboli,E; Tzoulaki,I] Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, United Kingdom. [Romaguera,D] Instituto de Investigación Sanitaria de Palma (IdISPa), Palma de Mallorca, Spain. [Romaguera,D; Quirós,J; Sánchez-Cantalejo,E; Etxezarreta,N; Huerta,JM; Barricarte,A; Bonet,C] CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain. [Peelen,LM; Schouw,ITV; Beulens,JWJ; Moons,KGM] Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands.[Freisling,H; Muller,DC; Ferrari,P; Huybrechts,I] International Agency for Research on Cancer, Lyon, France. [Fagherazz,G; Boutron-Ruault,M; Affret,A] Institut National de la Santé et de la Recherche Médicale, Center for Research in Epidemiology and Population, Health, Villejuif, France. Institut Gustave Roussy, Villejuif, France. Paris South University, Unité Mixte de Recherche, Villejuif, France. [Overvad,K; Dahm,CC] Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus, Denmark. [Olsen,A; Roswall,N] Danish Cancer Society, Institute of Cancer Epidemiology, Copenhagen, Denmark. [Tsilidis,KK] German Cancer Research Center (DKFZ), Division of Cancer Epidemiology, Heidelberg, Germany. [Katzke,VA; Kühn,T] Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke German Institute of Human Nutrition, Potsdam, Germany. [Buijsse,B] Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece. [Quirós,R] Public Health Directorate, Asturias, Oviedo, Spain. [Sánchez-Cantalejo,E] Andalusian School of Public Health, Granada, Spain. [Etxezarreta,N] Public Health Direction and Biodonostia Basque Regional Health Department, San Sebastian, Spain. [Huerta,JM] Department of Epidemiology, Murcia Regional Health Council, Murcia, Spain. [Barricarte,A] Navarre Public Health Institute, Pamplona, Spain. [Bonet,C] Unit of Nutrition, Environment and Cancer, Catalan Institute of Oncology, Barcelona, Spain. [Khaw,K] University of Cambridge School of Clinical Medicine, Clinical Gerontology Unit, Cambridge, United Kingdom. [Key,J] Cancer Epidemiology Unit, Nuffield Department of Clinical Medicine, University of Oxford, United Kingdom. [Trichopoulou,A; Bamia,C; Lagiou,P] Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece. Hellenic Health Foundation, Athens, Greece. [Palli,D] Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute—ISPO, Florence, Italy. [Agnoli,C] Epidemiology and Prevention Unit, Department of Preventive and Predictive Medicine, Foundation of the Carlo Besta Neurological Institute, Milan, Italy. [Tumino,R] Cancer Registry and Histopathology Unit, “Civic MP Arezzo” Hospital, Ragusa, Italy. [Fasanelli,F] Human Genetics Foundation, Turin, Italy. [Bueno-de-Mesquita,HB; Boer,JMA] Center for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment, Bilthoven, Netherlands. [Sonestedt,E] Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden. [Nilsson,LM; Renström,F] Department of Public Health and Clinical Medicine, Nutritional Research, Umeå University, Umeå, Sweden. [Weiderpass,E; Skeie,G; Lund,E] Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway. [Weiderpass,E] Department of Research, Cancer Registry of Norway, Oslo, Norway. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. Genetic Epidemiology Group, Folkhälsan Research Center, Helsinki,
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