%0 Journal Article
%A Lassale, Camille
%A Gunter, Marc J
%A Romaguera, Dora
%A Peelen, Linda M
%A Van der Schouw, Yvonne T
%A Beulens, Joline W J
%A Freisling, Heinz
%A Muller, David C
%A Ferrari, Pietro
%A Huybrechts, Inge
%A Fagherazzi, Guy
%A Boutron-Ruault, Marie-Christine
%A Affret, Aurélie
%A Overvad, Kim
%A Dahm, Christina C
%A Olsen, Anja
%A Roswall, Nina
%A Tsilidis, Konstantinos K
%A Katzke, Verena A
%A Kühn, Tilman
%A Buijsse, Brian
%A Quirós, José-Ramón
%A Sánchez-Cantalejo, Emilio
%A Etxezarreta, Nerea
%A Huerta, José María
%A Barricarte, Aurelio
%A Bonet, Catalina
%A Khaw, Kay-Tee
%A Key, Timothy J
%A Trichopoulou, Antonia
%A Bamia, Christina
%A Lagiou, Pagona
%A Palli, Domenico
%A Agnoli, Claudia
%A Tumino, Rosario
%A Fasanelli, Francesca
%A Panico, Salvatore
%A Bueno-de-Mesquita, H Bas
%A Boer, Jolanda M A
%A Sonestedt, Emily
%A Nilsson, Lena Maria
%A Renström, Frida
%A Weiderpass, Elisabete
%A Skeie, Guri
%A Lund, Eiliv
%A Moons, Karel G M
%A Riboli, Elio
%A Tzoulaki, Ioanna
%T Diet Quality Scores and Prediction of All-Cause, Cardiovascular and Cancer Mortality in a Pan-European Cohort Study.
%D 2016
%U http://hdl.handle.net/10668/2384
%X Scores of overall diet quality have received increasing attention in relation to disease aetiology; however, their value in risk prediction has been little examined. The objective was to assess and compare the association and predictive performance of 10 diet quality scores on 10-year risk of all-cause, CVD and cancer mortality in 451,256 healthy participants to the European Prospective Investigation into Cancer and Nutrition, followed-up for a median of 12.8y. All dietary scores studied showed significant inverse associations with all outcomes. The range of HRs (95% CI) in the top vs. lowest quartile of dietary scores in a composite model including non-invasive factors (age, sex, smoking, body mass index, education, physical activity and study centre) was 0.75 (0.72-0.79) to 0.88 (0.84-0.92) for all-cause, 0.76 (0.69-0.83) to 0.84 (0.76-0.92) for CVD and 0.78 (0.73-0.83) to 0.91 (0.85-0.97) for cancer mortality. Models with dietary scores alone showed low discrimination, but composite models also including age, sex and other non-invasive factors showed good discrimination and calibration, which varied little between different diet scores examined. Mean C-statistic of full models was 0.73, 0.80 and 0.71 for all-cause, CVD and cancer mortality. Dietary scores have poor predictive performance for 10-year mortality risk when used in isolation but display good predictive ability in combination with other non-invasive common risk factors.
%K Sistema cardiovascular
%K Estudios de cohortes
%K Dieta
%K Hábitos alimenticios
%K Neoplasias
%K Estado Nutricional
%K Estudios Prospectivos
%K Factores de Riesgo
%K Hábito de Fumar
%K Índice de masa corporal
%K Actividad motora
%~