RT Journal Article T1 Diet Quality Scores and Prediction of All-Cause, Cardiovascular and Cancer Mortality in a Pan-European Cohort Study. A1 Lassale, Camille A1 Gunter, Marc J A1 Romaguera, Dora A1 Peelen, Linda M A1 Van der Schouw, Yvonne T A1 Beulens, Joline W J A1 Freisling, Heinz A1 Muller, David C A1 Ferrari, Pietro A1 Huybrechts, Inge A1 Fagherazzi, Guy A1 Boutron-Ruault, Marie-Christine A1 Affret, Aurélie A1 Overvad, Kim A1 Dahm, Christina C A1 Olsen, Anja A1 Roswall, Nina A1 Tsilidis, Konstantinos K A1 Katzke, Verena A A1 Kühn, Tilman A1 Buijsse, Brian A1 Quirós, José-Ramón A1 Sánchez-Cantalejo, Emilio A1 Etxezarreta, Nerea A1 Huerta, José María A1 Barricarte, Aurelio A1 Bonet, Catalina A1 Khaw, Kay-Tee A1 Key, Timothy J A1 Trichopoulou, Antonia A1 Bamia, Christina A1 Lagiou, Pagona A1 Palli, Domenico A1 Agnoli, Claudia A1 Tumino, Rosario A1 Fasanelli, Francesca A1 Panico, Salvatore A1 Bueno-de-Mesquita, H Bas A1 Boer, Jolanda M A A1 Sonestedt, Emily A1 Nilsson, Lena Maria A1 Renström, Frida A1 Weiderpass, Elisabete A1 Skeie, Guri A1 Lund, Eiliv A1 Moons, Karel G M A1 Riboli, Elio A1 Tzoulaki, Ioanna K1 Sistema cardiovascular K1 Estudios de cohortes K1 Dieta K1 Hábitos alimenticios K1 Neoplasias K1 Estado Nutricional K1 Estudios Prospectivos K1 Factores de Riesgo K1 Hábito de Fumar K1 Índice de masa corporal K1 Actividad motora AB Scores of overall diet quality have received increasing attention in relation to disease aetiology; however, their value in risk prediction has been little examined. The objective was to assess and compare the association and predictive performance of 10 diet quality scores on 10-year risk of all-cause, CVD and cancer mortality in 451,256 healthy participants to the European Prospective Investigation into Cancer and Nutrition, followed-up for a median of 12.8y. All dietary scores studied showed significant inverse associations with all outcomes. The range of HRs (95% CI) in the top vs. lowest quartile of dietary scores in a composite model including non-invasive factors (age, sex, smoking, body mass index, education, physical activity and study centre) was 0.75 (0.72-0.79) to 0.88 (0.84-0.92) for all-cause, 0.76 (0.69-0.83) to 0.84 (0.76-0.92) for CVD and 0.78 (0.73-0.83) to 0.91 (0.85-0.97) for cancer mortality. Models with dietary scores alone showed low discrimination, but composite models also including age, sex and other non-invasive factors showed good discrimination and calibration, which varied little between different diet scores examined. Mean C-statistic of full models was 0.73, 0.80 and 0.71 for all-cause, CVD and cancer mortality. Dietary scores have poor predictive performance for 10-year mortality risk when used in isolation but display good predictive ability in combination with other non-invasive common risk factors. PB Public Library of Science YR 2016 FD 2016-07-13 LK http://hdl.handle.net/10668/2384 UL http://hdl.handle.net/10668/2384 LA en NO Lassale C, Gunter MJ, Romaguera D, Peelen LM, Van der Schouw YT, Beulens JW, et al. Diet Quality Scores and Prediction of All-Cause, Cardiovascular and Cancer Mortality in a Pan-European Cohort Study. PLoS ONE 2016; 11(7):e0159025 NO Journal Article; DS RISalud RD Apr 11, 2025