Publication: Successful Adaptation of Bee Venom Immunotherapy in a Patient Monosensitized to Api m 10.
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Identifiers
Date
2020-02-25
Authors
Ruiz-Leon, B
Navas, A
Serrano, P
Espinazo, M
Labrador-Horrillo, M
Monsalve, R I
Jurado, A
Moreno-Aguilar, C
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
Esmon Publicidad
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Abstract
Bee venom immunotherapy (BVIT), although highly effective, does not protect 10%-15% of patients allergic to bee stings [1]. Even though the production of allergenic extracts is standardized, the real content of major components is not completely known, given the total content of allergenic proteins and the enzymatic activity of phospholipase A2 (Api m 1) and hyaluronidase (Api m 2). To date, 12 allergens have been described as components of Apis mellifera venom (AMV). Api m 1, Api m 2, Api m 3, Api m 5, and Api m 10 are considered major allergens, and their specific IgE (sIgE) can be determined using commercially available techniques [1].
Description
MeSH Terms
Allergens
Basophil Degranulation Test
Bee Venoms
Beekeeping
Desensitization, Immunologic
Humans
Hypersensitivity
Immune Tolerance
Immunization
Immunoglobulin E
Insect Bites and Stings
Male
Middle Aged
Occupational Exposure
Basophil Degranulation Test
Bee Venoms
Beekeeping
Desensitization, Immunologic
Humans
Hypersensitivity
Immune Tolerance
Immunization
Immunoglobulin E
Insect Bites and Stings
Male
Middle Aged
Occupational Exposure
DeCS Terms
Alérgenos
Apicultura
Desensibilización inmunológica
Exposición profesional
Hipersensibilidad
Inmunización
Inmunoglobulina E
Mordeduras y picaduras de insectos
Apicultura
Desensibilización inmunológica
Exposición profesional
Hipersensibilidad
Inmunización
Inmunoglobulina E
Mordeduras y picaduras de insectos
CIE Terms
Keywords
Api m 10, Bee venom allergy, Effectiveness of venom immunotherapy, Molecular diagnosis
Citation
Ruiz-León B, Navas A, Serrano P, Espinazo M, Labrador-Horrillo M, Monsalve RI, et al. Successful Adaptation of Bee Venom Immunotherapy in a Patient Monosensitized to Api m 10. J Investig Allergol Clin Immunol. 2020;30(4):296-298