RT Journal Article T1 Successful Adaptation of Bee Venom Immunotherapy in a Patient Monosensitized to Api m 10. A1 Ruiz-Leon, B A1 Navas, A A1 Serrano, P A1 Espinazo, M A1 Labrador-Horrillo, M A1 Monsalve, R I A1 Jurado, A A1 Moreno-Aguilar, C K1 Api m 10 K1 Bee venom allergy K1 Effectiveness of venom immunotherapy K1 Molecular diagnosis AB Bee venom immunotherapy (BVIT), although highly effective, does not protect 10%-15% of patients allergic to bee stings [1]. Even though the production of allergenic extracts is standardized, the real content of major components is not completely known, given the total content of allergenic proteins and the enzymatic activity of phospholipase A2 (Api m 1) and hyaluronidase (Api m 2). To date, 12 allergens have been described as components of Apis mellifera venom (AMV). Api m 1, Api m 2, Api m 3, Api m 5, and Api m 10 are considered major allergens, and their specific IgE (sIgE) can be determined using commercially available techniques [1]. PB Esmon Publicidad SN 1018-9068 YR 2020 FD 2020-02-25 LK http://hdl.handle.net/10668/15163 UL http://hdl.handle.net/10668/15163 LA en NO Ruiz-León B, Navas A, Serrano P, Espinazo M, Labrador-Horrillo M, Monsalve RI, et al. Successful Adaptation of Bee Venom Immunotherapy in a Patient Monosensitized to Api m 10. J Investig Allergol Clin Immunol. 2020;30(4):296-298 DS RISalud RD Apr 11, 2025