Publication: Short- and Long-Term Prognosis of Patients With Takotsubo Syndrome Based on Different Triggers: Importance of the Physical Nature.
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Date
2019-12-13
Authors
Uribarri, Aitor
Núñez-Gil, Iván J
Conty, D Aritza
Vedia, Oscar
Almendro-Delia, Manuel
Duran Cambra, Albert
Martin-Garcia, Agustin C
Barrionuevo-Sánchez, Marisa
Martínez-Sellés, Manuel
Raposeiras-Roubín, Sergio
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Abstract
Background Takotsubo syndrome (TTS) is an acute reversible heart condition initially believed to represent a benign pathology attributable to its self-limiting clinical course; however, little is known about its prognosis based on different triggers. This study compared short- and long-term outcomes between TTS based on different triggers, focusing on various physical triggering events. Methods and Results We analyzed patients with a definitive TTS diagnosis recruited for the Spanish National Registry on TTS (RETAKO [Registry on Takotsubo Syndrome]). Short- and long-term outcomes were compared between different groups according to triggering factors. A total of 939 patients were included. An emotional trigger was detected in 340 patients (36.2%), a physical trigger in 293 patients (31.2%), and none could be identified in 306 patients (32.6%). The main physical triggers observed were infections (30.7%), followed by surgical procedures (22.5%), physical activities (18.4%), episodes of severe hypoxia (18.4%), and neurological events (9.9%). TTS triggered by physical factors showed higher mortality in the short and long term, and within this group, patients whose physical trigger was hypoxia were those who had a worse prognosis, in addition to being triggered by physical factors, including age >70 years, diabetes mellitus, left ventricular eyection fraction 70 years, diabetes mellitus, left ventricular eyection fraction
Description
MeSH Terms
Aged
Aged, 80 and over
Emotions
Female
Humans
Male
Middle Aged
Prognosis
Stress, Physiological
Stress, Psychological
Takotsubo Cardiomyopathy
Time Factors
Aged, 80 and over
Emotions
Female
Humans
Male
Middle Aged
Prognosis
Stress, Physiological
Stress, Psychological
Takotsubo Cardiomyopathy
Time Factors
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CIE Terms
Keywords
Takotsubo cardiomyopathy, broken heart syndrome, classification, outcome, stress, stress‐induced cardiomyopathy