%0 Journal Article
%A Uribarri, Aitor
%A Núñez-Gil, Iván J
%A Conty, D Aritza
%A Vedia, Oscar
%A Almendro-Delia, Manuel
%A Duran Cambra, Albert
%A Martin-Garcia, Agustin C
%A Barrionuevo-Sánchez, Marisa
%A Martínez-Sellés, Manuel
%A Raposeiras-Roubín, Sergio
%A Guillén, Marta
%A Garcia Acuña, Jose Maria
%A Matute-Blanco, Lucía
%A Linares Vicente, José A
%A Sánchez Grande Flecha, Alejandro
%A Andrés, Mireia
%A Pérez-Castellanos, Alberto
%A Lopez-Pais, Javier
%A RETAKO Investigators
%T Short- and Long-Term Prognosis of Patients With Takotsubo Syndrome Based on Different Triggers: Importance of the Physical Nature.
%D 2019
%U http://hdl.handle.net/10668/14820
%X Background Takotsubo syndrome (TTS) is an acute reversible heart condition initially believed to represent a benign pathology attributable to its self-limiting clinical course; however, little is known about its prognosis based on different triggers. This study compared short- and long-term outcomes between TTS based on different triggers, focusing on various physical triggering events. Methods and Results We analyzed patients with a definitive TTS diagnosis recruited for the Spanish National Registry on TTS (RETAKO [Registry on Takotsubo Syndrome]). Short- and long-term outcomes were compared between different groups according to triggering factors. A total of 939 patients were included. An emotional trigger was detected in 340 patients (36.2%), a physical trigger in 293 patients (31.2%), and none could be identified in 306 patients (32.6%). The main physical triggers observed were infections (30.7%), followed by surgical procedures (22.5%), physical activities (18.4%), episodes of severe hypoxia (18.4%), and neurological events (9.9%). TTS triggered by physical factors showed higher mortality in the short and long term, and within this group, patients whose physical trigger was hypoxia were those who had a worse prognosis, in addition to being triggered by physical factors, including age >70 years, diabetes mellitus, left ventricular eyection fraction 70 years, diabetes mellitus, left ventricular eyection fraction
%K Takotsubo cardiomyopathy
%K broken heart syndrome
%K classification
%K outcome
%K stress
%K stress‐induced cardiomyopathy
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