RT Journal Article
T1 Short- and Long-Term Prognosis of Patients With Takotsubo Syndrome Based on Different Triggers: Importance of the Physical Nature.
A1 Uribarri, Aitor
A1 Núñez-Gil, Iván J
A1 Conty, D Aritza
A1 Vedia, Oscar
A1 Almendro-Delia, Manuel
A1 Duran Cambra, Albert
A1 Martin-Garcia, Agustin C
A1 Barrionuevo-Sánchez, Marisa
A1 Martínez-Sellés, Manuel
A1 Raposeiras-Roubín, Sergio
A1 Guillén, Marta
A1 Garcia Acuña, Jose Maria
A1 Matute-Blanco, Lucía
A1 Linares Vicente, José A
A1 Sánchez Grande Flecha, Alejandro
A1 Andrés, Mireia
A1 Pérez-Castellanos, Alberto
A1 Lopez-Pais, Javier
A1 RETAKO Investigators, 
K1 Takotsubo cardiomyopathy
K1 broken heart syndrome
K1 classification
K1 outcome
K1 stress
K1 stress‐induced cardiomyopathy
AB Background Takotsubo syndrome (TTS) is an acute reversible heart condition initially believed to represent a benign pathology attributable to its self-limiting clinical course; however, little is known about its prognosis based on different triggers. This study compared short- and long-term outcomes between TTS based on different triggers, focusing on various physical triggering events. Methods and Results We analyzed patients with a definitive TTS diagnosis recruited for the Spanish National Registry on TTS (RETAKO [Registry on Takotsubo Syndrome]). Short- and long-term outcomes were compared between different groups according to triggering factors. A total of 939 patients were included. An emotional trigger was detected in 340 patients (36.2%), a physical trigger in 293 patients (31.2%), and none could be identified in 306 patients (32.6%). The main physical triggers observed were infections (30.7%), followed by surgical procedures (22.5%), physical activities (18.4%), episodes of severe hypoxia (18.4%), and neurological events (9.9%). TTS triggered by physical factors showed higher mortality in the short and long term, and within this group, patients whose physical trigger was hypoxia were those who had a worse prognosis, in addition to being triggered by physical factors, including age >70 years, diabetes mellitus, left ventricular eyection fraction 70 years, diabetes mellitus, left ventricular eyection fraction
YR 2019
FD 2019-12-13
LK http://hdl.handle.net/10668/14820
UL http://hdl.handle.net/10668/14820
LA en
DS RISalud
RD Apr 5, 2025