Publication: Health-related quality of life in patients newly diagnosed with prostate cancer: CAPLIFE study.
dc.contributor.author | Lozano-Lorca, Macarena | |
dc.contributor.author | Barrios-Rodriguez, Rocio | |
dc.contributor.author | Redondo-Sanchez, Daniel | |
dc.contributor.author | Cozar, Jose-Manuel | |
dc.contributor.author | Arrabal-Martin, Miguel | |
dc.contributor.author | Garcia-Caballos, Marta | |
dc.contributor.author | Salcedo-Bellido, Inmaculada | |
dc.contributor.author | Sanchez-Perez, Maria-Jose | |
dc.contributor.author | Jimenez-Moleon, Jose-Juan | |
dc.contributor.author | Olmedo-Requena, Rocio | |
dc.contributor.funder | Universidad de Granada / CBUA | |
dc.contributor.funder | Regional Ministry of Health and Families of Andalusia/Consejería de Salud y Familias de la Junta de Andalucía | |
dc.date.accessioned | 2023-05-03T13:44:34Z | |
dc.date.available | 2023-05-03T13:44:34Z | |
dc.date.issued | 2022-11-21 | |
dc.description.abstract | To analyse the Health-Related Quality of Life (HRQoL) at diagnosis of patients with prostate cancer (PCa) according to tumour extension and urinary symptomatology and to explore factors associated with HRQoL. 408 Controls and 463 PCa cases were included. Eligibility criteria were a new diagnosis of PCa (cases), 40-80 years of age, and residence in the participating hospitals' coverage area for ≥ 6 months before recruitment. HRQoL was evaluated using the 12-Item Short-Form Health Survey, Mental (MCS) and Physical Component Summaries (PCS), and urinary symptoms with the International Prostate Symptom Score. HRQoL scores for all PCa cases, according to tumour extension and urinary symptoms, were compared with controls. In addition, information about lifestyles and comorbidities was collected and its association with low HRQoL (lower scores) were explored using logistic regression models. Overall cases had similar PCS score, but lower MCS score than controls. The lowest standardised scores for both PCS and MCS were reached by cases with severe urinary symptoms and a metastatic tumour [mean (SD); PCS: 41.9 (11.5), MCS: 42.3 (10.3)]. Having "below" PCS and MCS scores was associated with the presence of three or more comorbidities in the cases [aOR = 2.86 (1.19-6.84) for PCS and aOR = 3.58 (1.37-9.31) for MCS] and with severe urinary symptomatology [aOR = 4.71 (1.84-12.08) for PCS and aOR = 7.63 (2.70-21.58) for MCS]. The mental dimension of HRQoL at diagnosis of patients with PCa was lower than in controls, especially for cases with severe urinary symptoms and a metastatic tumour. Comorbidities and urinary symptoms were variables associated with the HRQoL of PCa cases. | |
dc.description.version | Si | |
dc.identifier.citation | Lozano-Lorca M, Barrios-Rodríguez R, Redondo-Sánchez D, Cózar JM, Arrabal-Martín M, García-Caballos M, et al. Health-related quality of life in patients newly diagnosed with prostate cancer: CAPLIFE study. Qual Life Res. 2023 Apr;32(4):977-988. | |
dc.identifier.doi | 10.1007/s11136-022-03302-z | |
dc.identifier.essn | 1573-2649 | |
dc.identifier.pmc | PMC10063519 | |
dc.identifier.pmid | 36409391 | |
dc.identifier.pubmedURL | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063519/pdf | |
dc.identifier.unpaywallURL | https://link.springer.com/content/pdf/10.1007/s11136-022-03302-z.pdf | |
dc.identifier.uri | http://hdl.handle.net/10668/20708 | |
dc.issue.number | 4 | |
dc.journal.title | Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation | |
dc.journal.titleabbreviation | Qual Life Res | |
dc.language.iso | en | |
dc.organization | Hospital Universitario San Cecilio | |
dc.organization | Hospital Universitario Virgen de las Nieves | |
dc.organization | Granada | |
dc.organization | Metropolitano de Granada | |
dc.organization | Escuela Andaluza de Salud Pública-EASP | |
dc.organization | Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA) | |
dc.page.number | 977-988 | |
dc.provenance | Realizada la curación de contenido 23/08/2024 | |
dc.publisher | Springer Dordrecht | |
dc.pubmedtype | Journal Article | |
dc.relation.projectID | PI-0514-2016 | |
dc.relation.publisherversion | https://doi.org/10.1007/s11136-022-03302-z | |
dc.rights | Attribution 4.0 International | |
dc.rights.accessRights | open access | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.subject | Health-related quality of life | |
dc.subject | Prostate cancer | |
dc.subject | Tumour extension | |
dc.subject | Urinary symptomatology | |
dc.subject.decs | Calidad de vida | |
dc.subject.decs | Comorbilidad | |
dc.subject.decs | Encuestas epidemiológicas | |
dc.subject.decs | Estilo de vida | |
dc.subject.decs | Humanos | |
dc.subject.decs | Masculino | |
dc.subject.decs | Neoplasias de la próstata | |
dc.subject.mesh | Male | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Quality of Life | |
dc.subject.mesh | Prostatic Neoplasms | |
dc.subject.mesh | Comorbidity | |
dc.subject.mesh | Life Style | |
dc.subject.mesh | Health Surveys | |
dc.title | Health-related quality of life in patients newly diagnosed with prostate cancer: CAPLIFE study. | |
dc.type | research article | |
dc.type.hasVersion | VoR | |
dc.volume.number | 32 | |
dspace.entity.type | Publication |