Publication: Effect of a Lifestyle Intervention Program With Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial.
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Identifiers
Date
2018-09-29
Authors
Salas-Salvado, Jordi
Diaz-Lopez, Andres
Ruiz-Canela, Miguel
Basora, Josep
Fito, Montse
Corella, Dolores
Serra-Majem, Luis
Wärnberg, Julia
Romaguera, Dora
Estruch, Ramon
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
American Diabetes Association
Abstract
The long-term impact of intentional weight loss on cardiovascular events remains unknown. We describe 12-month changes in body weight and cardiovascular risk factors in PREvención con DIeta MEDiterránea (PREDIMED)-Plus, a trial designed to evaluate the long-term effectiveness of an intensive weight loss lifestyle intervention on primary cardiovascular prevention. Overweight/obese adults with metabolic syndrome aged 55-75 years (n = 626) were randomized to an intensive weight loss lifestyle intervention based on an energy-restricted Mediterranean diet, physical activity promotion, and behavioral support (IG) or a control group (CG). The primary and secondary outcomes were changes in weight and cardiovascular risk markers, respectively. Diet and physical activity changes were in the expected direction, with significant improvements in IG versus CG. After 12 months, IG participants lost an average of 3.2 kg vs. 0.7 kg in the CG (P PREDIMED-Plus intensive lifestyle intervention for 12 months was effective in decreasing adiposity and improving cardiovascular risk factors in overweight/obese older adults with metabolic syndrome, as well as in individuals with or at risk for diabetes.
Description
MeSH Terms
Aged
Diet, mediterranean
Exercise
Exercise therapy
Female
Follow-up studies
Humans
Life style
Male
Metabolic syndrome
Middle aged
Obesity
Overweight
Prediabetic state
Risk factors
Weight loss
Diet, mediterranean
Exercise
Exercise therapy
Female
Follow-up studies
Humans
Life style
Male
Metabolic syndrome
Middle aged
Obesity
Overweight
Prediabetic state
Risk factors
Weight loss
DeCS Terms
Dieta mediterránea
Ejercicio físico
Estado prediabético
Estilo de vida
Factores de riesgo
Obesidad
Pérdida de peso
Síndrome metabólico
Terapia por ejercicio
Ejercicio físico
Estado prediabético
Estilo de vida
Factores de riesgo
Obesidad
Pérdida de peso
Síndrome metabólico
Terapia por ejercicio
CIE Terms
Keywords
Behavior therapy, Blood glucose, Caloric restriction, Cardiovascular diseases
Citation
Salas-Salvadó J, Díaz-López A, Ruiz-Canela M, Basora J, Fitó M, Corella D, et al. Effect of a Lifestyle Intervention Program With Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial. Diabetes Care. 2019 May;42(5):777-78