RT Journal Article
T1 Effect of a Lifestyle Intervention Program With Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial.
A1 Salas-Salvado, Jordi
A1 Diaz-Lopez, Andres
A1 Ruiz-Canela, Miguel
A1 Basora, Josep
A1 Fito, Montse
A1 Corella, Dolores
A1 Serra-Majem, Luis
A1 Wärnberg, Julia
A1 Romaguera, Dora
A1 Estruch, Ramon
A1 Vidal, Josep
A1 Martinez, J Alfredo
A1 Aros, Fernando
A1 Vazquez, Clotilde
A1 Ros, Emilio
A1 Vioque, Jesus
A1 Lopez-Miranda, Jose
A1 Bueno-Cavanillas, Aurora
A1 Tur, Josep A
A1 Tinahones, Francisco J
A1 Martin, Vicente
A1 Lapetra, Jose
A1 Pinto, Xavier
A1 Daimiel, Lidia
A1 Delgado-Rodriguez, Miguel
A1 Matia, Pilar
A1 Gomez-Gracia, Enrique
A1 Diez-Espino, Javier
A1 Babio, Nancy
A1 Castañer, Olga
A1 Sorli, Jose V
A1 Fiol, Miquel
A1 Zulet, Maria Angeles
A1 Bullo, Monica
A1 Goday, Albert
A1 Martinez-Gonzalez, Miguel A
K1 Behavior therapy
K1 Blood glucose
K1 Caloric restriction
K1 Cardiovascular diseases
AB The long-term impact of intentional weight loss on cardiovascular events remains unknown. We describe 12-month changes in body weight and cardiovascular risk factors in PREvención con DIeta MEDiterránea (PREDIMED)-Plus, a trial designed to evaluate the long-term effectiveness of an intensive weight loss lifestyle intervention on primary cardiovascular prevention. Overweight/obese adults with metabolic syndrome aged 55-75 years (n = 626) were randomized to an intensive weight loss lifestyle intervention based on an energy-restricted Mediterranean diet, physical activity promotion, and behavioral support (IG) or a control group (CG). The primary and secondary outcomes were changes in weight and cardiovascular risk markers, respectively. Diet and physical activity changes were in the expected direction, with significant improvements in IG versus CG. After 12 months, IG participants lost an average of 3.2 kg vs. 0.7 kg in the CG (P  PREDIMED-Plus intensive lifestyle intervention for 12 months was effective in decreasing adiposity and improving cardiovascular risk factors in overweight/obese older adults with metabolic syndrome, as well as in individuals with or at risk for diabetes.
PB American Diabetes Association
YR 2018
FD 2018-09-29
LK http://hdl.handle.net/10668/13151
UL http://hdl.handle.net/10668/13151
LA en
NO Salas-Salvadó J, Díaz-López A, Ruiz-Canela M, Basora J, Fitó M, Corella D, et al. Effect of a Lifestyle Intervention Program With Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial. Diabetes Care. 2019 May;42(5):777-78
DS RISalud
RD Apr 26, 2025