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Effect of a Lifestyle Intervention Program With Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial.

dc.contributor.authorSalas-Salvado, Jordi
dc.contributor.authorDiaz-Lopez, Andres
dc.contributor.authorRuiz-Canela, Miguel
dc.contributor.authorBasora, Josep
dc.contributor.authorFito, Montse
dc.contributor.authorCorella, Dolores
dc.contributor.authorSerra-Majem, Luis
dc.contributor.authorWärnberg, Julia
dc.contributor.authorRomaguera, Dora
dc.contributor.authorEstruch, Ramon
dc.contributor.authorVidal, Josep
dc.contributor.authorMartinez, J Alfredo
dc.contributor.authorAros, Fernando
dc.contributor.authorVazquez, Clotilde
dc.contributor.authorRos, Emilio
dc.contributor.authorVioque, Jesus
dc.contributor.authorLopez-Miranda, Jose
dc.contributor.authorBueno-Cavanillas, Aurora
dc.contributor.authorTur, Josep A
dc.contributor.authorTinahones, Francisco J
dc.contributor.authorMartin, Vicente
dc.contributor.authorLapetra, Jose
dc.contributor.authorPinto, Xavier
dc.contributor.authorDaimiel, Lidia
dc.contributor.authorDelgado-Rodriguez, Miguel
dc.contributor.authorMatia, Pilar
dc.contributor.authorGomez-Gracia, Enrique
dc.contributor.authorDiez-Espino, Javier
dc.contributor.authorBabio, Nancy
dc.contributor.authorCastañer, Olga
dc.contributor.authorSorli, Jose V
dc.contributor.authorFiol, Miquel
dc.contributor.authorZulet, Maria Angeles
dc.contributor.authorBullo, Monica
dc.contributor.authorGoday, Albert
dc.contributor.authorMartinez-Gonzalez, Miguel A
dc.contributor.funderISCIII, through the Fondo de Investigacion para la Salud (FIS)
dc.contributor.funderEuropean Regional Development Fund
dc.contributor.funderEuropean Research Council
dc.contributor.funderConsejería de Salud de la Junta de Andalucía
dc.contributor.groupPREDIMED-Plus investigators
dc.date.accessioned2023-01-25T10:24:02Z
dc.date.available2023-01-25T10:24:02Z
dc.date.issued2018-09-29
dc.description.abstractThe long-term impact of intentional weight loss on cardiovascular events remains unknown. We describe 12-month changes in body weight and cardiovascular risk factors in PREvención con DIeta MEDiterránea (PREDIMED)-Plus, a trial designed to evaluate the long-term effectiveness of an intensive weight loss lifestyle intervention on primary cardiovascular prevention. Overweight/obese adults with metabolic syndrome aged 55-75 years (n = 626) were randomized to an intensive weight loss lifestyle intervention based on an energy-restricted Mediterranean diet, physical activity promotion, and behavioral support (IG) or a control group (CG). The primary and secondary outcomes were changes in weight and cardiovascular risk markers, respectively. Diet and physical activity changes were in the expected direction, with significant improvements in IG versus CG. After 12 months, IG participants lost an average of 3.2 kg vs. 0.7 kg in the CG (P PREDIMED-Plus intensive lifestyle intervention for 12 months was effective in decreasing adiposity and improving cardiovascular risk factors in overweight/obese older adults with metabolic syndrome, as well as in individuals with or at risk for diabetes.
dc.description.versionSi
dc.identifier.citationSalas-Salvadó J, Díaz-López A, Ruiz-Canela M, Basora J, Fitó M, Corella D, et al. Effect of a Lifestyle Intervention Program With Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial. Diabetes Care. 2019 May;42(5):777-78
dc.identifier.doi10.2337/dc18-0836
dc.identifier.essn1935-5548
dc.identifier.pmid30389673
dc.identifier.unpaywallURLhttps://care.diabetesjournals.org/content/diacare/42/5/777.full.pdf
dc.identifier.urihttp://hdl.handle.net/10668/13151
dc.issue.number5
dc.journal.titleDiabetes care
dc.language.isoen
dc.organizationHospital Universitario Reina Sofía
dc.organizationInstituto Maimónides de Investigación Biomédica de Córdoba-IMIBIC
dc.organizationHospital Universitario Virgen de la Victoria
dc.organizationInstituto de Investigación Biomédica de Málaga-IBIMA
dc.page.number777-788
dc.publisherAmerican Diabetes Association
dc.pubmedtypeJournal Article
dc.pubmedtypeRandomized Controlled Trial
dc.pubmedtypeResearch Support, Non-U.S. Gov't
dc.relation.projectIDPI13/00673
dc.relation.projectIDPI13/00492
dc.relation.projectIDPI0458/2013
dc.relation.projectIDPS0358/2016
dc.relation.projectIDJR17/00022
dc.relation.publisherversionhttps://diabetesjournals.org/care/article-lookup/doi/10.2337/dc18-0836
dc.rights.accessRightsopen access
dc.subjectBehavior therapy
dc.subjectBlood glucose
dc.subjectCaloric restriction
dc.subjectCardiovascular diseases
dc.subject.decsDieta mediterránea
dc.subject.decsEjercicio físico
dc.subject.decsEstado prediabético
dc.subject.decsEstilo de vida
dc.subject.decsFactores de riesgo
dc.subject.decsObesidad
dc.subject.decsPérdida de peso
dc.subject.decsSíndrome metabólico
dc.subject.decsTerapia por ejercicio
dc.subject.meshAged
dc.subject.meshDiet, mediterranean
dc.subject.meshExercise
dc.subject.meshExercise therapy
dc.subject.meshFemale
dc.subject.meshFollow-up studies
dc.subject.meshHumans
dc.subject.meshLife style
dc.subject.meshMale
dc.subject.meshMetabolic syndrome
dc.subject.meshMiddle aged
dc.subject.meshObesity
dc.subject.meshOverweight
dc.subject.meshPrediabetic state
dc.subject.meshRisk factors
dc.subject.meshWeight loss
dc.titleEffect of a Lifestyle Intervention Program With Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number42
dspace.entity.typePublication

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