Publication: Superinfection during treatment of nosocomial infections with tigecycline
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Date
2010-05-16
Authors
García-Cabrera, Emilio
Gómez-Gómez, M J
Ortiz-Leyba, C
Pachón, J
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Springer
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Abstract
We performed a retrospective and observational study of 51 patients treated with tigecycline, as the treatment for nosocomial infections due to multidrug-resistant microorganisms, to evaluate the superinfection rate and their etiologies. Superinfections were diagnosed in 12 (23.5%) patients (seven due to Pseudomonas aeruginosa, 13.7%) and one patient had P. aeruginosa colonization. Five patients with superinfection died (41.6%), three due to superinfections and two to underlying diseases. The superinfection rate observed during tigecycline treatment is higher than that previously reported. Pseudomonas aeruginosa is the most frequent agent, being the cause of 58.5% of all superinfections.
Description
MeSH Terms
Superinfection
Tigecycline
Nosocomial Infections
Multidrug-Resistant Organisms
Pseudomonas aeruginosa
Tigecycline
Nosocomial Infections
Multidrug-Resistant Organisms
Pseudomonas aeruginosa
DeCS Terms
Sobreinfección
Tigeciclina
Infecciones Nosocomiales
Organismos Multirresistentes a Medicamentos
Pseudomonas aeruginosa
Tigeciclina
Infecciones Nosocomiales
Organismos Multirresistentes a Medicamentos
Pseudomonas aeruginosa
CIE Terms
Keywords
Minimum Inhibitory Concentration, Nosocomial Infection, Tigecycline, Acinetobacter Baumannii, Stenotrophomonas Maltophilia
Citation
García-Cabrera E, Jiménez-Mejías ME, Gil Navarro MV, Gómez-Gómez MJ, Ortiz-Leyba C, Cordero E, et al Superinfection during treatment of nosocomial infections with tigecycline. Eur J Clin Microbiol Infect Dis. 2010 Jul;29(7):867-7081