RT Journal Article T1 Superinfection during treatment of nosocomial infections with tigecycline A1 García-Cabrera, Emilio A1 Jiménez-Mejías, Manuel E. A1 Gil-Navarro, María Victoria A1 Gómez-Gómez, M J A1 Ortiz-Leyba, C A1 Cordero, Elisa A1 Pachón, J K1 Minimum Inhibitory Concentration K1 Nosocomial Infection K1 Tigecycline K1 Acinetobacter Baumannii K1 Stenotrophomonas Maltophilia AB We performed a retrospective and observational study of 51 patients treated with tigecycline, as the treatment for nosocomial infections due to multidrug-resistant microorganisms, to evaluate the superinfection rate and their etiologies. Superinfections were diagnosed in 12 (23.5%) patients (seven due to Pseudomonas aeruginosa, 13.7%) and one patient had P. aeruginosa colonization. Five patients with superinfection died (41.6%), three due to superinfections and two to underlying diseases. The superinfection rate observed during tigecycline treatment is higher than that previously reported. Pseudomonas aeruginosa is the most frequent agent, being the cause of 58.5% of all superinfections. PB Springer SN 2732-5326 YR 2010 FD 2010-05-16 LK https://hdl.handle.net/10668/28450 UL https://hdl.handle.net/10668/28450 LA en NO García-Cabrera E, Jiménez-Mejías ME, Gil Navarro MV, Gómez-Gómez MJ, Ortiz-Leyba C, Cordero E, et al Superinfection during treatment of nosocomial infections with tigecycline. Eur J Clin Microbiol Infect Dis. 2010 Jul;29(7):867-7081 NO This study was supported by the Spanish Network for Research in Infectious Diseases (REIPI RD06/0008, Instituto de Salud Carlos III-FEDER, Ministerio de Ciencia e Innovación). DS RISalud RD Apr 9, 2025