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Superinfection during treatment of nosocomial infections with tigecycline

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dc.contributor.authorGarcía-Cabrera, Emilio
dc.contributor.authorJiménez-Mejías, Manuel E.
dc.contributor.authorGil-Navarro, María Victoria
dc.contributor.authorGómez-Gómez, M J
dc.contributor.authorOrtiz-Leyba, C
dc.contributor.authorCordero, Elisa
dc.contributor.authorPachón, J
dc.contributor.authoraffiliation[García-Cabrera,E; Jiménez-Mejías,ME; Gil Navarro,MV; Gómez-Gómez,MJ; Ortiz-Leyba,C; Cordero,E; Pachón,J] Hospital Universitario Virgen del Rocío, Seville, Spain.
dc.contributor.funderInstituto de Salud Carlos III-FEDER
dc.contributor.funderMinisterio de Ciencia e Innovación
dc.date.accessioned2025-01-27T11:01:57Z
dc.date.available2025-01-27T11:01:57Z
dc.date.issued2010-05-16
dc.description.abstractWe performed a retrospective and observational study of 51 patients treated with tigecycline, as the treatment for nosocomial infections due to multidrug-resistant microorganisms, to evaluate the superinfection rate and their etiologies. Superinfections were diagnosed in 12 (23.5%) patients (seven due to Pseudomonas aeruginosa, 13.7%) and one patient had P. aeruginosa colonization. Five patients with superinfection died (41.6%), three due to superinfections and two to underlying diseases. The superinfection rate observed during tigecycline treatment is higher than that previously reported. Pseudomonas aeruginosa is the most frequent agent, being the cause of 58.5% of all superinfections.
dc.description.sponsorshipThis study was supported by the Spanish Network for Research in Infectious Diseases (REIPI RD06/0008, Instituto de Salud Carlos III-FEDER, Ministerio de Ciencia e Innovación).
dc.description.versionYes
dc.identifier.citationGarcía-Cabrera E, Jiménez-Mejías ME, Gil Navarro MV, Gómez-Gómez MJ, Ortiz-Leyba C, Cordero E, et al Superinfection during treatment of nosocomial infections with tigecycline. Eur J Clin Microbiol Infect Dis. 2010 Jul;29(7):867-7081
dc.identifier.doi10.1007/s10096-010-0942-y
dc.identifier.issn2732-5326
dc.identifier.pmid20473700
dc.identifier.urihttps://hdl.handle.net/10668/28450
dc.issue.number7
dc.journal.titleEuropean Journal of Clinical Microbiology & Infectious Diseases
dc.language.isoen
dc.page.number867–871
dc.publisherSpringer
dc.relation.projectIDinfo:eu-repo/grantAgreement/MSC//RD06%2F0008%2F1019/ES/RED ESPAÑOLA DE INVESTIGACIÓN EN PATOLOGÍA INFECCIOSA (REIPI)/
dc.relation.publisherversionhttps://link.springer.com/article/10.1007/s10096-010-0942-y
dc.rights.accessRightsrestricted access
dc.subjectMinimum Inhibitory Concentration
dc.subjectNosocomial Infection
dc.subjectTigecycline
dc.subjectAcinetobacter Baumannii
dc.subjectStenotrophomonas Maltophilia
dc.subject.decsSobreinfección
dc.subject.decsTigeciclina
dc.subject.decsInfecciones Nosocomiales
dc.subject.decsOrganismos Multirresistentes a Medicamentos
dc.subject.decsPseudomonas aeruginosa
dc.subject.meshSuperinfection
dc.subject.meshTigecycline
dc.subject.meshNosocomial Infections
dc.subject.meshMultidrug-Resistant Organisms
dc.subject.meshPseudomonas aeruginosa
dc.titleSuperinfection during treatment of nosocomial infections with tigecycline
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number29
dspace.entity.typePublication
relation.isAuthorOfPublication45ac47a6-0d45-4062-a061-df6954b46e05
relation.isAuthorOfPublication17f063a5-687d-4b26-8a34-8f7c5fd72752
relation.isAuthorOfPublication2bff13b6-cee6-481a-a573-e6cc975924a9
relation.isAuthorOfPublication.latestForDiscovery45ac47a6-0d45-4062-a061-df6954b46e05

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