Publication: Cocoa polyphenols and inflammatory markers of cardiovascular disease.
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Date
2014-02
Authors
Khan, Nasiruddin
Khymenets, Olha
Urpí-Sardà, Mireia
Tulipani, Sara
García-Aloy, Mar
Monagas, María
Mora-Cubillos, Ximena
Llorach, Rafael
Andrés-Lacueva, Cristina
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Abstract
Epidemiological studies have demonstrated the beneficial effect of plant-derived food intake in reducing the risk of cardiovascular disease (CVD). The potential bioactivity of cocoa and its polyphenolic components in modulating cardiovascular health is now being studied worldwide and continues to grow at a rapid pace. In fact, the high polyphenol content of cocoa is of particular interest from the nutritional and pharmacological viewpoints. Cocoa polyphenols are shown to possess a range of cardiovascular-protective properties, and can play a meaningful role through modulating different inflammatory markers involved in atherosclerosis. Accumulated evidence on related anti-inflammatory effects of cocoa polyphenols is summarized in the present review.
Description
Journal Article; Research Support, Non-U.S. Gov't;
MeSH Terms
Medical Subject Headings::Diseases::Cardiovascular Diseases
Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Inflammation
Medical Subject Headings::Diseases::Cardiovascular Diseases::Vascular Diseases::Arterial Occlusive Diseases::Arteriosclerosis
Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Phenols::Polyphenols
Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Pharmacokinetics::Biological Availability
Medical Subject Headings::Organisms::Eukaryota::Plants::Viridiplantae::Streptophyta::Embryophyta::Angiosperms::Sterculiaceae::Cacao
Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers::Biomarkers, Pharmacological
Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Inflammation
Medical Subject Headings::Diseases::Cardiovascular Diseases::Vascular Diseases::Arterial Occlusive Diseases::Arteriosclerosis
Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Phenols::Polyphenols
Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Pharmacokinetics::Biological Availability
Medical Subject Headings::Organisms::Eukaryota::Plants::Viridiplantae::Streptophyta::Embryophyta::Angiosperms::Sterculiaceae::Cacao
Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers::Biomarkers, Pharmacological
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Keywords
Cocoa polyphenols, Bioavailability, Inflammation, CVD, Enfermedades Cardiovasculares, Inflamación, Aterosclerosis, Polifenoles, Disponibilidad Biológica, Cacao
Citation
Khan N, Khymenets O, Urpí-Sardà M, Tulipani S, Garcia-Aloy M, Monagas M, et al. Cocoa polyphenols and inflammatory markers of cardiovascular disease. Nutrients. 2014; 6(2):844-80