Publication:
SEOM-GEMCAD-TTD clinical guidelines for localized rectal cancer (2021).

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Date

2022-02-22

Authors

Capdevila, Jaume
Gomez, Ma Auxiliadora
Guillot, Monica
Paez, David
Pericay, Carles
Safont, Maria Jose
Tarazona, Noelia
Vera, Ruth
Vidal, Joana
Sastre, Javier

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Springer
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Abstract

The management of localized rectal cancer requires a multidisciplinary approach to optimize outcomes, reduce morbidity and prevent under or overtreatments. While early stages may obtain benefit of local resections without any additional therapies, locally advanced rectal cancer becomes a challenge defining the better sequential strategy of surgery, radiotherapy and chemotherapy. The latest results of international phase III studies have positioned the total neoadjuvant therapy as a potential new standard of care in high risk rectal cancers, however, the best schedule is still not well defined.

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MeSH Terms

Antineoplastic combined chemotherapy protocols
Chemoradiotherapy
Humans
Neoadjuvant therapy
Neoplasm staging
Neoplasms, second primary
Rectal neoplasms
Rectum

DeCS Terms

Estadificación de neoplasias
Neoplasias primarias secundarias
Neoplasias del recto
Protocolos de quimioterapia combinada antineoplásica
Quimioradioterapia
Recto
Terapia neoadyuvante

CIE Terms

Keywords

Guideline, Rectal cancer, Total neoadjuvant therapy

Citation

Capdevila J, Gómez MA, Guillot M, Páez D, Pericay C, Safont MJ, et al. SEOM-GEMCAD-TTD clinical guidelines for localized rectal cancer (2021). Clin Transl Oncol. 2022 Apr;24(4):646-657. doi: 10.1007/s12094-022-02816-9. Epub 2022 Mar 18. Erratum in: Clin Transl Oncol. 2022 Jul;24(7):1443-1444