%0 Journal Article %A Capdevila, Jaume %A Gomez, Ma Auxiliadora %A Guillot, Monica %A Paez, David %A Pericay, Carles %A Safont, Maria Jose %A Tarazona, Noelia %A Vera, Ruth %A Vidal, Joana %A Sastre, Javier %T SEOM-GEMCAD-TTD clinical guidelines for localized rectal cancer (2021). %D 2022 %U http://hdl.handle.net/10668/21130 %X The management of localized rectal cancer requires a multidisciplinary approach to optimize outcomes, reduce morbidity and prevent under or overtreatments. While early stages may obtain benefit of local resections without any additional therapies, locally advanced rectal cancer becomes a challenge defining the better sequential strategy of surgery, radiotherapy and chemotherapy. The latest results of international phase III studies have positioned the total neoadjuvant therapy as a potential new standard of care in high risk rectal cancers, however, the best schedule is still not well defined. %K Guideline %K Rectal cancer %K Total neoadjuvant therapy %~