Editorial: Hypoxia and Cardiorespiratory Control.

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Date

2021-12-22

Authors

Okada, Yasumasa
Paton, Julian F R
Lopez-Barneo, Jose
Wilson, Richard J A
Marina, Nephtali
Pokorski, Mieczyslaw

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Abstract

To maintain adequate oxygen levels in the body, which is essential for a healthy life , the respiratory and cardiovascular systems play vitally important roles . When the oxygen content is insufficient, i.e., when hypoxia is loaded, respiratory and cardiovascular systems respond to restore, compensate, or adapt to hypoxia , e.g., by increasing ventilation and blood flow to maintain oxygen transport to vital organs. Traditionally, it has been thought that hypoxia is detected solely by carotid and aortic bodies , i.e., by peripheral chemoreceptors, and information from the peripheral chemoreceptors is transmitted to respiratory and cardiovascular centers in the brainstem whose respiratory and cardiovascular neural outputs are regulated.

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MeSH Terms

Aortic Bodies
Oxygen
Hypoxia
Cardiovascular System
Brain Stem

DeCS Terms

Hipoxia
Oxígeno
Pensamiento
Tronco Encefálico
Cuerpos aórticos
Transferencia de oxígeno

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Keywords

TRPA1, astrocyte, carotid body, intermittent hypoxia, plasticity, pulmonary hypertension, sleep apnea, sympathetic excitation

Citation

Okada Y, Paton JFR, López-Barneo J, Wilson RJA, Marina N, Pokorski M. Editorial: Hypoxia and Cardiorespiratory Control. Front Physiol. 2021 Dec 22;12:820815.