RT Generic T1 Editorial: Hypoxia and Cardiorespiratory Control. A1 Okada, Yasumasa A1 Paton, Julian F R A1 Lopez-Barneo, Jose A1 Wilson, Richard J A A1 Marina, Nephtali A1 Pokorski, Mieczyslaw K1 TRPA1 K1 astrocyte K1 carotid body K1 intermittent hypoxia K1 plasticity K1 pulmonary hypertension K1 sleep apnea K1 sympathetic excitation AB To maintain adequate oxygen levels in the body, which is essential for a healthy life , the respiratory and cardiovascular systems play vitally important roles . When the oxygen content is insufficient, i.e., when hypoxia is loaded, respiratory and cardiovascular systems respond to restore, compensate, or adapt to hypoxia , e.g., by increasing ventilation and blood flow to maintain oxygen transport to vital organs. Traditionally, it has been thought that hypoxia is detected solely by carotid and aortic bodies , i.e., by peripheral chemoreceptors, and information from the peripheral chemoreceptors is transmitted to respiratory and cardiovascular centers in the brainstem whose respiratory and cardiovascular neural outputs are regulated. SN 1664-042X YR 2021 FD 2021-12-22 LK https://hdl.handle.net/10668/27836 UL https://hdl.handle.net/10668/27836 LA en NO Okada Y, Paton JFR, López-Barneo J, Wilson RJA, Marina N, Pokorski M. Editorial: Hypoxia and Cardiorespiratory Control. Front Physiol. 2021 Dec 22;12:820815. DS RISalud RD Apr 12, 2025