Recommendations for antibiotic selection for severe nosocomial infections
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Date
2021-10-01
Authors
Mensa, Josep
Barberan, Jose
Ferrer, Ricard
Borges, Marcio
Rascado, Pedro
Maseda, Emilio
Oliver, Antonio
Marco, Francesc
Adalia, Ramon
Aguilar, Gerardo
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Sociedad espanola quimioterapia
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Abstract
Severe infection and its evolution to sepsis are becoming more prevalent every day and are among the leading causes of critical illness and mortality. Proper management is crucial to improve prognosis. This document addresses three essential points that have a significant impact on this objective: a) early recognition of patients with sepsis criteria, b) identification of those patients who suffer from an infection and have a high risk of progressing to sepsis, and c) adequate selection and optimization of the initial antimicrobial treatment.
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sepsis, septic shock, severe infection, selection and optimization of antimicrobial treatment, ceftazidime-avibactam, ceftolozane-tazobactam, meropenem, C-reactive protein, Blood-stream infections, International consensus definitions, Klebsiella-pneumoniae infection, Community-acquired pneumonia, Intensive-care units, Acute kidney injury, Septic shock, Severe sepsis, Antimicrobial therapy