RT Journal Article T1 Recommendations for antibiotic selection for severe nosocomial infections A1 Mensa, Josep A1 Barberan, Jose A1 Ferrer, Ricard A1 Borges, Marcio A1 Rascado, Pedro A1 Maseda, Emilio A1 Oliver, Antonio A1 Marco, Francesc A1 Adalia, Ramon A1 Aguilar, Gerardo A1 Estella, Angel A1 Leon Lopez, Rafael A1 Robles Marcos, Manuel S. A1 Gonzalez de Molina, Fco J. A1 Serrano Garcia, Ricardo A1 Salavert, Miguel A1 Fernandez Gomez, Javier A1 Poliakova, Yuliya A1 Pasquau, Juan A1 Ramon Azanza, Jose A1 Bou Arevalo, German A1 LLinares Mondejar, Pedro A1 Cardinal-Fernandez, Pablo A1 Soriano, Alex K1 sepsis K1 septic shock K1 severe infection K1 selection and optimization of antimicrobial treatment K1 ceftazidime-avibactam K1 ceftolozane-tazobactam K1 meropenem K1 C-reactive protein K1 Blood-stream infections K1 International consensus definitions K1 Klebsiella-pneumoniae infection K1 Community-acquired pneumonia K1 Intensive-care units K1 Acute kidney injury K1 Septic shock K1 Severe sepsis K1 Antimicrobial therapy AB Severe infection and its evolution to sepsis are becoming more prevalent every day and are among the leading causes of critical illness and mortality. Proper management is crucial to improve prognosis. This document addresses three essential points that have a significant impact on this objective: a) early recognition of patients with sepsis criteria, b) identification of those patients who suffer from an infection and have a high risk of progressing to sepsis, and c) adequate selection and optimization of the initial antimicrobial treatment. PB Sociedad espanola quimioterapia SN 0214-3429 YR 2021 FD 2021-10-01 LK https://hdl.handle.net/10668/25097 UL https://hdl.handle.net/10668/25097 LA en DS RISalud RD Apr 7, 2025