Effect of omega-3 fatty acids on hypoalbuminemia in acute heart failure patients with increased inflammatory activity
dc.contributor.author | Bonilla Palomas, Juan Luis | |
dc.contributor.author | Gamez Lopez, Antonio Luis | |
dc.contributor.author | Moreno Conde, Mirian | |
dc.contributor.author | Lopez Ibanez, Maria Cristina | |
dc.contributor.author | Moreno Villar, Maria Amparo | |
dc.contributor.authoraffiliation | [Bonilla Palomas, Juan Luis] Hosp San Juan de la Cruz, Unidad Gest & Clin Med Interne, Area Cardiol, Ave Linares S-N, Jaen 23400, Spain | |
dc.contributor.authoraffiliation | [Gamez Lopez, Antonio Luis] Hosp San Juan de la Cruz, Unidad Gest & Clin Med Interne, Area Cardiol, Ave Linares S-N, Jaen 23400, Spain | |
dc.contributor.authoraffiliation | [Moreno Conde, Mirian] Hosp San Juan de la Cruz, Unidad Gest Clin Med Interna, Jaen, Spain | |
dc.contributor.authoraffiliation | [Lopez Ibanez, Maria Cristina] Hosp San Juan de la Cruz, Unidad Gest Clin Med Interna, Jaen, Spain | |
dc.contributor.authoraffiliation | [Moreno Villar, Maria Amparo] Hosp San Juan de la Cruz, Unidad Gest Clin Farm, Jaen, Spain | |
dc.date.accessioned | 2025-01-07T14:40:22Z | |
dc.date.available | 2025-01-07T14:40:22Z | |
dc.date.issued | 2021-09-01 | |
dc.description.abstract | Introduction: inflammatory activity (IA) is a cause of hypoalbuminemia in patients with acute heart failure (AHF).Objectives: the main objective of this study was to evaluate whether an AI modulator treatment contributes to correcting albuminemia in this context.Methods: in this clinical trial 43 patients with AHF, hypoalbuminemia (serum albumin = 25 mg/l] were randomly assigned to receive omega-3 fatty acids (4 g daily) or placebo for 4 weeks. Albuminemia and CRP were reassessed at weeks 1 and 4. An analysis of variance for repeated measures was performed.Results: mean age was 75.6 +/- 8.8 years, 72.1 % were male, and the most frequent etiology was ischemic (46.5 %). The two groups were homogeneous in their baseline characteristics. A significant increase in albumin concentration was found at week 4 from baseline (p for the effect of time | |
dc.identifier.doi | 10.20960/nh.03637 | |
dc.identifier.essn | 1699-5198 | |
dc.identifier.issn | 0212-1611 | |
dc.identifier.pmid | 34154367 | |
dc.identifier.unpaywallURL | https://www.nutricionhospitalaria.org/filesPortalWeb/27/MA-00027-01.pdf?uMNu82MMWoDsb55gx9B04pEeObqNSrZX | |
dc.identifier.uri | https://hdl.handle.net/10668/26573 | |
dc.identifier.wosID | 754885100002 | |
dc.issue.number | 5 | |
dc.journal.title | Nutricion hospitalaria | |
dc.journal.titleabbreviation | Nutr. hosp. | |
dc.language.iso | es | |
dc.organization | SAS - Hospital San Agustín | |
dc.page.number | 890-896 | |
dc.publisher | Aran ediciones, s l | |
dc.rights | Attribution-ShareAlike 4.0 International | |
dc.rights.accessRights | open access | |
dc.rights.uri | http://creativecommons.org/licenses/by-sa/4.0/ | |
dc.subject | Heart failure | |
dc.subject | Hypoalbuminemia | |
dc.subject | Inflammatory activity | |
dc.subject | Omega-3 polyunsaturated fatty acids | |
dc.subject | Clinical trial | |
dc.subject | Polyunsaturated fatty-acids | |
dc.subject | Levels predict survival | |
dc.subject | Necrosis-factor-alpha | |
dc.subject | Serum-albumin | |
dc.subject | European-society | |
dc.subject | Protein | |
dc.subject | Activation | |
dc.subject | Receptors | |
dc.subject | Mortality | |
dc.subject | Diagnosis | |
dc.title | Effect of omega-3 fatty acids on hypoalbuminemia in acute heart failure patients with increased inflammatory activity | |
dc.type | research article | |
dc.type.hasVersion | VoR | |
dc.volume.number | 38 | |
dc.wostype | Article |