Trajectories of alcohol consumption during life and the risk of developing breast cancer.

dc.contributor.authorDonat-Vargas, Carolina
dc.contributor.authorGuerrero-Zotano, Ángel
dc.contributor.authorCasas, Ana
dc.contributor.authorBaena-Cañada, José Manuel
dc.contributor.authorLope, Virginia
dc.contributor.authorAntolín, Silvia
dc.contributor.authorGarcia-Saénz, José Ángel
dc.contributor.authorBermejo, Begoña
dc.contributor.authorMuñoz, Montserrat
dc.contributor.authorRamos, Manuel
dc.contributor.authorde Juan, Ana
dc.contributor.authorJara Sánchez, Carlos
dc.contributor.authorSánchez-Rovira, Pedro
dc.contributor.authorAntón, Antonio
dc.contributor.authorBrunet, Joan
dc.contributor.authorGavilá, Joaquín
dc.contributor.authorSalvador, Javier
dc.contributor.authorArriola Arellano, Esperanza
dc.contributor.authorBezares, Susana
dc.contributor.authorFernández de Larrea-Baz, Nerea
dc.contributor.authorPérez-Gómez, Beatriz
dc.contributor.authorMartín, Miguel
dc.contributor.authorPollán, Marina
dc.date.accessioned2025-01-07T13:10:15Z
dc.date.available2025-01-07T13:10:15Z
dc.date.issued2021-09-06
dc.description.abstractWhether there are lifetime points of greater sensitivity to the deleterious effects of alcohol intake on the breasts remains inconclusive. To compare the influence of distinctive trajectories of alcohol consumption throughout a woman's life on development of breast cancer (BC). 1278 confirmed invasive BC cases and matched (by age and residence) controls from the Epi-GEICAM study (Spain) were used. The novel group-based trajectory modelling was used to identify different alcohol consumption trajectories throughout women's lifetime. Four alcohol trajectories were identified. The first comprised women (45%) with low alcohol consumption ( The greater the alcohol consumption accumulated throughout life, the greater the risk of BC, especially in postmenopausal women. Alcohol consumption during adolescence may particularly influence BC risk.
dc.identifier.doi10.1038/s41416-021-01492-w
dc.identifier.essn1532-1827
dc.identifier.pmcPMC8505448
dc.identifier.pmid34483338
dc.identifier.pubmedURLhttps://pmc.ncbi.nlm.nih.gov/articles/PMC8505448/pdf
dc.identifier.unpaywallURLhttps://www.nature.com/articles/s41416-021-01492-w.pdf
dc.identifier.urihttps://hdl.handle.net/10668/25305
dc.issue.number8
dc.journal.titleBritish journal of cancer
dc.journal.titleabbreviationBr J Cancer
dc.language.isoen
dc.organizationSAS - Hospital Universitario Puerta del Mar
dc.organizationSAS - Hospital Universitario Virgen del Rocío
dc.organizationSAS - Hospital Universitario de Jaén
dc.organizationSAS - Hospital Universitario Puerta del Mar
dc.organizationInstituto de Investigación e Innovación Biomédica de Cádiz (INiBICA)
dc.page.number1168-1176
dc.pubmedtypeComparative Study
dc.pubmedtypeJournal Article
dc.pubmedtypeMulticenter Study
dc.pubmedtypeResearch Support, Non-U.S. Gov't
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.meshAdolescent
dc.subject.meshAdult
dc.subject.meshAlcohol Drinking
dc.subject.meshBreast Neoplasms
dc.subject.meshCase-Control Studies
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMiddle Aged
dc.subject.meshPostmenopause
dc.subject.meshPremenopause
dc.subject.meshRisk Factors
dc.subject.meshSpain
dc.subject.meshSurveys and Questionnaires
dc.subject.meshYoung Adult
dc.titleTrajectories of alcohol consumption during life and the risk of developing breast cancer.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number125

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