Good Metabolic Control in Children with Type 1 Diabetes Mellitus: Does Glycated Hemoglobin Correlate with Interstitial Glucose Monitoring Using FreeStyle Libre?
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Date
2021-11-01
Authors
Porcel-Chacon, Rocio
Antunez-Fernandez, Cristina
Mora Loro, Maria
Ariza-Jimenez, Ana-Belen
Tapia Ceballos, Leopoldo
Jimenez Hinojosa, Jose Manuel
Lopez-Siguero, Juan Pedro
Leiva Gea, Isabel
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Publisher
Mdpi
Abstract
Background: Good metabolic control of Type 1 diabetes (T1D) leads to a reduction in complications. The only validated parameter for establishing the degree of control is glycated hemoglobin (HbA1c). We examined the relationship between HbA1c and a continuous glucose monitoring (CGM) system. Materials and methods: A cohort prospective study with 191 pediatric patients with T1D was conducted. Time in range (TIR), time below range (TBR), coefficient of variation (CV), number of capillary blood glucose tests, and HbA1c before sensor insertion and at one year of use were collected. Results: Patients were classified into five groups according to HbA1c at one year of using CGM. They performed fewer capillary blood glucose test at one year using CGM (-6 +/- 2, p
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Keywords
type 1 diabetes mellitus, pediatric diabetes, continuous glucose monitoring, time in 28 range, HbA1c, capillary blood glucose test, Sensing technology, Multicenter, Management