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Título : Posttreatment follow-Up of brucellosis by PCR assay.
Autor : Morata, Pilar
Queipo-Ortuño, María Isabel
Reguera, José María
García-Ordoñez, Miguel Angel
Pichardo, Cristina
Colmenero, Juan de Dios
Filiación: [Morata,P; Queipo-Ortuño, MI] Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Malaga. [Reguera,JM; García-Ordoñez,MA; Colmenero,J de D] Infectious Diseases Unit, Department of Internal Medicine, “Carlos Haya” Hospital, Malaga. [Pichardo,C] Infectious Diseases Service, “Virgen del Rocío” University Hospital, Seville, Spain.
Palabras clave : Aglutinación
Estudios de cohortes
Prueba de Coombs
Medios de cultivo
ADN bacteriano
Reacción en cadena de la polimerasa
Resultado del tratamiento
MeSH: Medical Subject Headings::Named Groups::Persons::Age Groups::Adult
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Aged
Medical Subject Headings::Phenomena and Processes::Immune System Phenomena::Immune System Processes::Antigen-Antibody Reactions::Agglutination
Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Anti-Bacterial Agents
Medical Subject Headings::Anatomy::Fluids and Secretions::Body Fluids::Blood
Medical Subject Headings::Organisms::Bacteria::Gram-Negative Bacteria::Gram-Negative Aerobic Bacteria::Gram-Negative Aerobic Rods and Cocci::Brucellaceae::Brucella
Medical Subject Headings::Diseases::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Negative Bacterial Infections::Brucellosis
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Immunologic Tests::Serologic Tests::Agglutination Tests::Hemagglutination Tests
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Equipment and Supplies::Culture Media
Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA::DNA, Bacterial
Medical Subject Headings::Check Tags::Female
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Check Tags::Male
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Nucleic Acid Amplification Techniques::Polymerase Chain Reaction
Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Recurrence
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcome
Medical Subject Headings::Named Groups::Persons::Age Groups::Adolescent
Fecha de publicación : Dec-1999
Editorial : American Society for Microbiology
Cita Bibliográfica: Morata P, Queipo-Ortuño MI, Reguera JM, García-Ordoñez MA, Pichardo C, Colmenero JD. Posttreatment follow-Up of brucellosis by PCR assay. J Clin Microbiol. 1999; 37(12):4163-6
Abstract: In order to evaluate the usefulness of a peripheral blood PCR assay in the posttreatment follow-up of brucellosis, a cohort of 30 patients was studied by means of blood cultures, rose Bengal, seroagglutination, Coombs' antibrucella tests, and PCR assay at the time of diagnosis, at the end of treatment, and 2, 4, and 6 months later. Of the 29 patients whose PCR assays were initially positive, 28 (96.5%) were negative at the conclusion of the treatment. PCR was positive for the two patients who had relapses and negative for another four who had suspected but unconfirmed relapses. PCR was negative for 98.3% of the follow-up samples from those patients who had a favorable evolution. In conclusion, PCR appears to be a very useful technique, not only for the initial diagnosis of the disease, but also for posttreatment follow-up and the early detection of relapses.
Descripción : Journal Article; Research Support, Non-U.S. Gov't;
Versión del editor :
ISSN : 1098-660X (Online)
0095-1137 (Print)
Appears in Collections:01- Artículos - Hospital Virgen del Rocío
01- Artículos - Hospital Regional de Málaga

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