RT Journal Article
T1 Posttreatment follow-Up of brucellosis by PCR assay.
A1 Morata, Pilar
A1 Queipo-Ortuño, María Isabel
A1 Reguera, José María
A1 García-Ordoñez, Miguel Angel
A1 Pichardo, Cristina
A1 Colmenero, Juan de Dios
K1 Aglutinación
K1 Antibacterianos
K1 Sangre
K1 Brucela
K1 Brucelosis
K1 Estudios de cohortes
K1 Prueba de Coombs
K1 Medios de cultivo
K1 ADN bacteriano
K1 Reacción en cadena de la polimerasa
K1 Recurrencia
K1 Resultado del tratamiento
AB In order to evaluate the usefulness of a peripheral blood PCR assay in the posttreatment follow-up of brucellosis, a cohort of 30 patients was studied by means of blood cultures, rose Bengal, seroagglutination, Coombs' antibrucella tests, and PCR assay at the time of diagnosis, at the end of treatment, and 2, 4, and 6 months later. Of the 29 patients whose PCR assays were initially positive, 28 (96.5%) were negative at the conclusion of the treatment. PCR was positive for the two patients who had relapses and negative for another four who had suspected but unconfirmed relapses. PCR was negative for 98.3% of the follow-up samples from those patients who had a favorable evolution. In conclusion, PCR appears to be a very useful technique, not only for the initial diagnosis of the disease, but also for posttreatment follow-up and the early detection of relapses.
PB American Society for Microbiology
SN 0095-1137
YR 1999
FD 1999-12
LK http://hdl.handle.net/10668/2327
UL http://hdl.handle.net/10668/2327
LA en
NO Morata P, Queipo-Ortuño MI, Reguera JM, García-Ordoñez MA, Pichardo C, Colmenero JD. Posttreatment follow-Up of brucellosis by PCR assay. J Clin Microbiol. 1999; 37(12):4163-6
NO Journal Article; Research Support, Non-U.S. Gov't;
DS RISalud
RD Apr 7, 2025