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http://hdl.handle.net/10668/2169
Title: | Long-term effects of varying consumption of ω3 fatty acids in ear, nose and throat cancer patients: assessment 1 year after radiotherapy. |
Authors: | Roca-Rodríguez, María del Mar García-Almeida, José Manuel Ruiz-Nava, Josefina Alcaide, Juan Lupiáñez-Pérez, Yolanda Rico-Pérez, José Manuel Toledo-Serrano, María Dolores Cardona, Fernando Medina-Carmona, José Antonio Tinahones, Francisco J |
metadata.dc.contributor.authoraffiliation: | [Roca-Rodríguez,MM; Alcaide,J; Cardona,F; Tinahones,FJ] Biomedical Research Institute of Málaga (IBIMA),Virgen de la Victoria Hospital, University of Málaga, Spain. [Roca-Rodríguez,MM; García-Almeida,JM; Ruiz-Nava,J; Tinahones,FJ] Department of Endocrinology and Nutrition, Virgen de la Victoria Hospital, Málaga, Spain. [Lupiáñez-Pérez,Y; Rico-Pérez,JM; Toledo-Serrano,MD; Medina Carmona,JA] Department of Clinical and Radiotherapeutic Oncology, Virgen de la Victoria Hospital, Málaga, Spain. [Roca-Rodríguez,MM; Cardona,F; Tinahones,FJ] Biomedical Research Center of Physiopathology of Obesity and Nutrition (CIBER CB06/003), Carlos III Health Institute. Madrid, Spain. |
Keywords: | Nutritional supplement;Cancer;Clinical study;Metabolic status;Survival;Antioxidantes;Marcadores biológicos;Índice de masa corporal;Proteina C reactiva;Suplementos dietéticos;Cáncer de oído;Electrolitos;Ácidos grasos insaturados;Glutatión peroxidasa;Peróxido de hidrógeno;Inflamación;Interleucina-6;Desnutrición;Neoplasias nasales;Estres oxidativo;Neoplasias faríngeas |
metadata.dc.subject.mesh: | Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Antioxidants Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers Medical Subject Headings::Health Care::Environment and Public Health::Public Health::Epidemiologic Measurements::Biometry::Anthropometry::Body Mass Index Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Albumins::C-Reactive Protein Medical Subject Headings::Technology, Industry, Agriculture::Food and Beverages::Food::Dietary Fiber Medical Subject Headings::Technology, Industry, Agriculture::Food and Beverages::Food::Dietary Supplements Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Head and Neck Neoplasms::Otorhinolaryngologic Neoplasms::Ear Neoplasms Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Electrolytes Medical Subject Headings::Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids, Unsaturated Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Peroxidases::Glutathione Peroxidase Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Electrolytes::Ions::Anions::Oxides::Peroxides::Hydrogen Peroxide Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Inflammation Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines::Interleukins::Interleukin-6 Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Malnutrition Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Head and Neck Neoplasms::Otorhinolaryngologic Neoplasms::Nose Neoplasms Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Oxidative Stress Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Head and Neck Neoplasms::Otorhinolaryngologic Neoplasms::Pharyngeal Neoplasms Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans |
Issue Date: | Feb-2015 |
Publisher: | Informa Healthcare |
Citation: | Roca-Rodríguez M del M, García-Almeida JM, Ruiz-Nava J, Alcaide J, Lupiañez-Pérez Y, Rico-Pérez JM, et al. Long-term effects of varying consumption of ω3 fatty acids in ear, nose and throat cancer patients: assessment 1 year after radiotherapy. Int J Food Sci Nutr. 2015; 66(1):108-13 |
Abstract: | Abstract A prospective 1-year follow-up study in ear, nose, and throat (ENT) cancer patients was carried out one year after radiotherapy to assess the effect of varying consumption of ω3 fatty acid according to whether they consumed more or less than the 50th percentile of ω3 fatty acids. Clinical, analytical, inflammatory (CRP and IL-6), and oxidative variables (TAC, GPx, GST, and SOD) were evaluated. The study comprised 31 patients (87.1% men), with a mean age of 61.3 ± 9.1 years. Hematological variables showed significant differences in the patients with a lower consumption of ω3 fatty acids. A lower mortality and longer survival were found in the group with ω3 fatty acid consumption ≥50th percentile but the differences were not significant. No significant difference was reached in toxicity, inflammation, and oxidative stress markers. The group with ω3 fatty acid consumption <50th percentile significantly experienced more hematological and immune changes. |
Description: | Journal Article; |
URI: | http://hdl.handle.net/10668/2169 |
metadata.dc.relation.publisherversion: | http://informahealthcare.com/doi/abs/10.3109/09637486.2014.953453 |
metadata.dc.identifier.doi: | 10.3109/09637486.2014.953453 |
ISSN: | 1465-3478 (Online) 0963-7486 (Print) |
Appears in Collections: | 01- Artículos - Hospital Virgen de la Victoria |
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Roca_Long_term.pdf | Pre-print (Versión del autor) | 493,07 kB | Adobe PDF | View/Open |
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