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http://hdl.handle.net/10668/1700| Title: | Accumulation of scandium in plasma in patients with chronic renal failure. |
| Authors: | Sánchez-González, Cristina López-Chaves, Carlos Rivas-García, Lorenzo Galindo, Pilar Gómez-Aracena, Jorge Aranda, Pilar Llopis, Juan |
| metadata.dc.contributor.authoraffiliation: | [Sánchez-González,C; López-Chaves,C; Rivas-García,L; Aranda,P; Llopis,J] Department of Physiology, University of Granada, Spain. [Galindo,P] Department of Nephrology, Virgen de las Nieves University Hospital, Granada, Spain. [Gómez-Aracena,J] Department of Preventive Medicine and Public Health, University of Málaga, Málaga, Spain. |
| Keywords: | Escandio;Adulto;Factores de Edad;Índice de Masa Corporal;Creatinina;Estudios Transversales;Progresión de la Enfermedad;Índices de Eritrocitos;Tasa de Filtración Glomerular;Humanos;Femenino;Masculino;Fallo Renal Crónico;Mediana Edad;Uremia;Adulto Joven;Adolescente |
| metadata.dc.subject.mesh: | Medical Subject Headings::Named Groups::Persons::Age Groups::Adult Medical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Age Factors Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Aged Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Mass Index Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Azoles::Imidazoles::Creatinine Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Disease Progression Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Hematologic Tests::Erythrocyte Indices Medical Subject Headings::Check Tags::Female Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Urological::Kidney Function Tests::Glomerular Filtration Rate Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans Medical Subject Headings::Diseases::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases::Renal Insufficiency::Renal Insufficiency, Chronic::Kidney Failure, Chronic Medical Subject Headings::Check Tags::Male Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Elements::Metals, Rare Earth::Scandium Medical Subject Headings::Diseases::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases::Uremia Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Young Adult Medical Subject Headings::Named Groups::Persons::Age Groups::Adolescent |
| Issue Date: | 12-Dec-2013 |
| Publisher: | Hindawi Publishing Corporation |
| Citation: | Sánchez-González C, López-Chaves C, Rivas-García L, Galindo P, Gómez-Aracena J, Aranda P, et al. Accumulation of scandium in plasma in patients with chronic renal failure. ScientificWorldJournal; 2013:782745 |
| Abstract: | Scandium (Sc) is an element with many industrial applications, but relatively little is known about its physiological and/or toxicological effects, and very little data are available concerning the role of Sc in chronic renal failure (CRF). This paper examines the changes in plasma levels of Sc in predialysis patients with CRF and the relationship with blood parameters. The participants in this trial were 48 patients with CRF in predialysis and 53 healthy controls. Erythrocyte, haemoglobin, and haematocrit counts in blood were determined, and levels of creatinine, urea, uric acid, albumin, total protein and Sc were measured in plasma. The glomerular filtration rate (GFR) was calculated using the Cockcroft-Gault index. The CRF patients were found to have higher plasma levels of creatinine, urea, uric acid, albumin, total protein, and Sc and a lower GFR than that the controls. Scandium in plasma was positively correlated with creatinine and plasma urea and negatively correlated with GFR, haemoglobin, and haematocrit and was associated with the risk of lower levels of erythrocytes, haemoglobin, and haematocrit. CRF was associated with increases in the circulating levels of scandium. |
| Description: | Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; |
| URI: | http://hdl.handle.net/10668/1700 |
| metadata.dc.relation.publisherversion: | http://www.hindawi.com/journals/tswj/2013/782745/abs/ |
| metadata.dc.identifier.doi: | 10.1155/2013/782745 |
| ISSN: | 1537-744X (Online) |
| Appears in Collections: | 01- Artículos - Hospital Virgen de las Nieves |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| SanchezGonzalez_AccumulationOfScandium.pdf | 1,11 MB | Adobe PDF | View/Open |
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