Publication:
Case Report: Acute-on-Chronic Liver Failure: Making the Diagnosis between Infection and Acute Alcoholic Hepatitis.

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Date

2016-05-12

Authors

Sendra, Carmen
Ampuero, Javier
Giraldez-Gallego, Alvaro
Sousa, Jose Manuel
Serrano-Jimenez, Maria
Romero-Gomez, Manuel

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Thieme Medical Publishers, Inc.
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Abstract

Acute-on-chronic liver failure (ACLF) represents a reversible syndrome associated with high short-term mortality, characterized by acute decompensation in patients with chronic liver disease and extrahepatic organ failure. Diagnosis and prognosis assessment is based on a newly developed diagnostic score, the Chronic Liver Failure Consortium Organ Failure score. Susceptibility to infections and systemic inflammation are typical triggers. The authors report a case in which a patient with alcohol-related cirrhosis was admitted to the hospital with acute decompensation and developed ACLF during hospitalization. This case led to an evaluation of the underlying process causing ACLF: infection versus acute alcoholic hepatitis.

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MeSH Terms

Acute-On-Chronic Liver Failure
Anti-Bacterial Agents
Diagnosis, Differential
Humans
Male
Organ Dysfunction Scores
Severity of Illness Index
Acute Kidney Injury
Administration, Intravenous
Bacterial Infections
Hepatitis, Alcoholic
Liver Cirrhosis, Alcoholic
Middle Aged
Radiography
Tomography, X-Ray Computed

DeCS Terms

Infecciones
Hospitales
Mortalidad
Hepatopatías
Diagnóstico
Pronóstico
Enfermedad hepática en estado terminal
Fibrosis

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Citation

Sendra C, Ampuero J, Gallego ÁG, Sousa JM, Jiménez MS, Romero-Gómez M. Case Report: Acute-on-Chronic Liver Failure: Making the Diagnosis between Infection and Acute Alcoholic Hepatitis. Semin Liver Dis. 2016 May;36(2):181-6.