Publication: Usefulness of the Hybrid RFR-FFR Approach: Results of a Prospective and Multicenter Analysis of Diagnostic Agreement between RFR and FFR-The RECOPA (REsting Full-Cycle Ratio Comparation versus Fractional Flow Reserve (A Prospective Validation)) Study
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Date
2021-03-31
Authors
Casanova-Sandoval, Juan
Fernandez-Rodriguez, Diego
Otaegui, Imanol
Gil Jimenez, Teresa
Rodriguez-Esteban, Marcos
Rivera, Kristian
Torres-Saura, Francisco
Jimenez Diaz, Victor
Ocaranza-Sanchez, Raymundo
Peral Disdier, Vicente
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Wiley-hindawi
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Abstract
Background. The resting full-cycle ratio (RFR) is a novel resting index which in contrast to the gold standard (fractional flow reserve (FFR)) does not require maximum hyperemia induction. The objectives of this study were to evaluate the agreement between RFR and FFR with the currently recommended thresholds and to design a hybrid RFR-FFR ischemia detection strategy, allowing a reduction of coronary vasodilator use. Materials and Methods. Patients subjected to invasive physiological study in 9 Spanish centers were prospectively recruited between April 2019 and March 2020. Sensitivity and specificity studies were made to assess diagnostic accuracy between the recommended levels of RFR
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Wave-free ratio, Invasive physiological indexes, Artery stenosis severity, Pressure measurements, Blood-flow, Coronary