Publication: Spontaneous macrocyclization through multiple dynamic cyclic aminal formation.
No Thumbnail Available
Identifiers
Date
2021
Authors
Carbajo, Daniel
Ruiz-Sánchez, Antonio Jesús
Nájera, Francisco
Pérez-Inestrosa, Ezequiel
Alfonso, Ignacio
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
Metrics
Export
Abstract
The use of aminals in dynamic covalent chemistry is slightly underexplored, probably due to their inherent instability. Here we report the spontaneous [2+2] macrocyclization of tetrakis(aminals). Their unexpected stability and structural modularity, the dynamic nature of the connections and their water tolerance make them appealing systems for future applications as stimulus-responsive materials.