%0 Journal Article %A Carbajo, Daniel %A Ruiz-Sánchez, Antonio Jesús %A Nájera, Francisco %A Pérez-Inestrosa, Ezequiel %A Alfonso, Ignacio %T Spontaneous macrocyclization through multiple dynamic cyclic aminal formation. %D 2021 %U http://hdl.handle.net/10668/16982 %X The use of aminals in dynamic covalent chemistry is slightly underexplored, probably due to their inherent instability. Here we report the spontaneous [2+2] macrocyclization of tetrakis(aminals). Their unexpected stability and structural modularity, the dynamic nature of the connections and their water tolerance make them appealing systems for future applications as stimulus-responsive materials. %~