Publication: MitoBlue as a tool to analyze the mitochondria-lysosome communication
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Identifiers
Date
2020-02-26
Authors
Sánchez, Mateo I.
Vida, Yolanda
Pérez-Inestrosa, Ezequiel
Mascareñas, José L.
Vázquez, M. Eugenio
Sugiura, Ayumu
Martínez-Costas, José
Advisors
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Volume Title
Publisher
Springer Nature
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Abstract
MitoBlue is a fluorescent bisamidine that can be used to easily monitor the changes in mitochondrial degradation processes in different cells and cellular conditions. MitoBlue staining pattern is exceptional among mitochondrial dyes and recombinant fluorescent probes, allowing the dynamic study of mitochondrial recycling in a variety of situations in living cells. MitoBlue is a unique tool for the study of these processes that will allow the detailed characterization of communication between mitochondria and lysosomes.
Description
MeSH Terms
Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amines::2-Naphthylamine
Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amidines
Medical Subject Headings::Organisms::Eukaryota::Animals
Medical Subject Headings::Anatomy::Embryonic Structures::Embryo, Nonmammalian::Chick Embryo
Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Fibroblasts
Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Cytoplasmic Vesicles::Lysosomes
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Microscopy::Microscopy, Fluorescence
Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Mitochondria
Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Specialty Uses of Chemicals::Laboratory Chemicals::Indicators and Reagents::Luminescent Agents::Fluorescent Dyes
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Clinical Laboratory Techniques::Histological Techniques::Histocytological Preparation Techniques::Staining and Labeling
Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amidines
Medical Subject Headings::Organisms::Eukaryota::Animals
Medical Subject Headings::Anatomy::Embryonic Structures::Embryo, Nonmammalian::Chick Embryo
Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Fibroblasts
Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Cytoplasmic Vesicles::Lysosomes
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Microscopy::Microscopy, Fluorescence
Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Mitochondria
Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Specialty Uses of Chemicals::Laboratory Chemicals::Indicators and Reagents::Luminescent Agents::Fluorescent Dyes
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Clinical Laboratory Techniques::Histological Techniques::Histocytological Preparation Techniques::Staining and Labeling
DeCS Terms
CIE Terms
Keywords
Mitochondrial degradation, Lysosome, Microscopy, Mitochondria, Proteins, Quality control, Mitofagia, Lisosomas, Microscopía, Mitocondrias, Proteínas, Control de calidad
Citation
Sánchez MI, Vida Y, Pérez-Inestrosa E, Mascareñas JL, Vázquez ME, Sugiura A, et al. MitoBlue as a tool to analyze the mitochondria-lysosome communication. Sci Rep. 2020 Feb 26;10(1):3528