Publication:
Fasting Glucose for the Diagnosis of Gestational Diabetes Mellitus (GDM) during the COVID-19 Pandemic.

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Date

2022-08-14

Authors

Gonzalez Gonzalez, Nieves Luisa
Gonzalez Davila, Enrique
Bugatto, Fernando
Vega-Guedes, Begoña
Pintado, Pilar
Tascon, L
Villalba Martin, Nazaret
Plasencia, Walter
Megia, Ana

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MDPI
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Abstract

Background: During the COVID-19 pandemic, different non-validated tests were proposed to simplify the diagnosis of gestational diabetes (GDM). Aim: To analyse the effects of replacing the two-step approach for Early-GDM and GDM diagnosis, with a fasting plasma glucose test. Material and Methods: This is a cohort study consisting of 3200 pregnant women: 400 with Early-GDM, 800 with GDM and 2000 with Non-GDM diagnosed using the two-step approach. Using fasting plasma glucose for Early-GDM and GDM diagnosis, according to the recommendations of Spain, Australia, Italy and the UK during the pandemic, the rates of missed and new Early-GDM and GDM were calculated and perinatal outcomes were analysed. Results: Using fasting plasma glucose in the first trimester >100 mg/dL for Early-GDM diagnosis, the rates of post-COVID missed and new Early-GDM were 79.5% and 3.2%, respectively. Using fasting plasma glucose at 24−28 weeks 100 mg/dL for Early-GDM diagnosis, the rates of post-COVID missed and new Early-GDM were 79.5% and 3.2%, respectively. Using fasting plasma glucose at 24−28 weeks 92, 95 or 100 mg/dL for GDM diagnosis, the rates of missed GDM were 50.4%, 78%, 82.6% and 92.4%, respectively, and 8.6%, 5.6% and 2.3% women with Non-GDM were diagnosed with new GDM. Conclusion: Fasting plasma glucose is not a good test for the diagnosis of GDM either in the first trimester or at 24−28 weeks.

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MeSH Terms

Blood Glucose
COVID-19
COVID-19 Testing
Cohort Studies
Diabetes, Gestational
Fasting
Female
Glucose
Glucose Tolerance Test
Humans
Male
Pandemics
Pregnancy

DeCS Terms

Ayuno
Diabetes gestacional
Embarazo
Glucemia
Glucosa
Pandemias
Prueba de COVID-19
Prueba de tolerancia a la glucosa

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Keywords

COVID-19 pandemic, Diagnosis, Early gestational diabetes, Fasting glucose, First trimester, Gestational diabetes, Gestational hyperglycemia, Perinatal outcomes

Citation

González González NL, González Dávila E, Bugatto F, Vega-Guedes B, Pintado P, Tascón L, et al. Fasting Glucose for the Diagnosis of Gestational Diabetes Mellitus (GDM) during the COVID-19 Pandemic. Nutrients. 2022 Aug 20;14(16):3432