Publication:
Suicidality in primary care patients who present with sadness and anhedonia: a prospective European study.

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Date

2016-04-06

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Moreno-Küstner, Berta
Jones, Rebeca
Švab, Igor
Maaroos, Heidi
Xavier, Miguel
Geerlings, Mirjam
Torres-González, Francisco
Nazareth, Irwin
Motrico-Martínez, Emma
Montón-Franco, Carmen

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Abstract

Sadness and anhedonia (loss of interest in activities) are central symptoms of major depression. However, not all people with these symptoms meet diagnostic criteria for major depression. We aimed to assess the importance of suicidality in the outcomes for primary care patients who present with sadness and anhedonia. Cohort study of 2,599 unselected primary care attenders in six European countries followed up at 6 and 12 months. 1) In patients with sadness and/or anhedonia who were not depressed at entry to the study, suicide plans (OR = 3.05; 95 % CI = 1.50-6.24; p = 0.0022) and suicide attempts (OR = 9.08; 95 % CI = 2.57-32.03; p = 0.0006) were significant predictors of developing new onset depression at 6 or 12 months. 2) In patients with sadness and/or anhedonia who met CIDI criteria for major depression at entry, suicidal ideation (OR = 2.93; 95 % CI = 1.70-5.07; p = 0.0001), suicide plans (OR = 3.70; 95 % CI = 2.08-6.57; p Three questions on suicidality could help primary care professionals to assess such patients more closely without necessarily establishing whether they meet criteria for major depression.

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Anhedonia
Cohort Studies
Depressive Disorder, Major
Europe
Female
Humans
Male
Middle Aged
Primary Health Care
Prospective Studies
Suicide

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Keywords

Anhedonia, Cohort, Depression, Primary care, Risk, Suicidality

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