RT Journal Article T1 Suicidality in primary care patients who present with sadness and anhedonia: a prospective European study. A1 Moreno-Küstner, Berta A1 Jones, Rebeca A1 Švab, Igor A1 Maaroos, Heidi A1 Xavier, Miguel A1 Geerlings, Mirjam A1 Torres-González, Francisco A1 Nazareth, Irwin A1 Motrico-Martínez, Emma A1 Montón-Franco, Carmen A1 Gil-de-Gómez, María José A1 Sánchez-Celaya, Marta A1 Díaz-Barreiros, Miguel Ángel A1 Vicens-Caldentey, Catalina A1 King, Michael K1 Anhedonia K1 Cohort K1 Depression K1 Primary care K1 Risk K1 Suicidality AB Sadness and anhedonia (loss of interest in activities) are central symptoms of major depression. However, not all people with these symptoms meet diagnostic criteria for major depression. We aimed to assess the importance of suicidality in the outcomes for primary care patients who present with sadness and anhedonia. Cohort study of 2,599 unselected primary care attenders in six European countries followed up at 6 and 12 months. 1) In patients with sadness and/or anhedonia who were not depressed at entry to the study, suicide plans (OR = 3.05; 95 % CI = 1.50-6.24; p = 0.0022) and suicide attempts (OR = 9.08; 95 % CI = 2.57-32.03; p = 0.0006) were significant predictors of developing new onset depression at 6 or 12 months. 2) In patients with sadness and/or anhedonia who met CIDI criteria for major depression at entry, suicidal ideation (OR = 2.93; 95 % CI = 1.70-5.07; p = 0.0001), suicide plans (OR = 3.70; 95 % CI = 2.08-6.57; p Three questions on suicidality could help primary care professionals to assess such patients more closely without necessarily establishing whether they meet criteria for major depression. YR 2016 FD 2016-04-06 LK http://hdl.handle.net/10668/9976 UL http://hdl.handle.net/10668/9976 LA en DS RISalud RD Apr 19, 2025