Publication:
Pain reduction of topical sevoflurane vs intravenous opioids in pressure ulcers.

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Date

2019-11-25

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Fernández-Ginés, F Dámaso
Cortiñas-Sáenz, Manuel
Agudo-Ponce, Desirée
Navajas-Gómez de Aranda, Ana
Morales-Molina, José A
Fernández-Sánchez, Carmen
Sierra-García, Francisco
Mateo-Carrasco, Héctor

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Abstract

Recently, it has been reported that topical irrigations of liquid sevoflurane on the bed of painful wounds produce a rapid, intense, and lasting analgesic effect. In this paper, A cohort of 112 patients with painful pressure ulcers who were refractory to opioids (or who exhibited undesirable adverse events to them) was treated with topical sevoflurane as per local institutional policy. These patients were recruited from an intensive care unit for a period of 3 years. The main aim was to determine the effectiveness of topical sevoflurane in reducing the pain of PUs and reducing the ulcer area. Study findings are reported and discussed herein and suggest that sevoflurane is a viable and promising treatment option for PUs.

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MeSH Terms

Administration, Intravenous
Administration, Topical
Adult
Aged
Aged, 80 and over
Analgesics, Opioid
Cohort Studies
Female
Humans
Male
Middle Aged
Pain
Platelet Aggregation Inhibitors
Pressure Ulcer
Prospective Studies
Sevoflurane
Spain

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Keywords

opioid, pain, pressure ulcer, sevoflurane, topical treatment

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