RT Journal Article T1 Pain reduction of topical sevoflurane vs intravenous opioids in pressure ulcers. A1 Fernández-Ginés, F Dámaso A1 Cortiñas-Sáenz, Manuel A1 Agudo-Ponce, Desirée A1 Navajas-Gómez de Aranda, Ana A1 Morales-Molina, José A A1 Fernández-Sánchez, Carmen A1 Sierra-García, Francisco A1 Mateo-Carrasco, Héctor K1 opioid K1 pain K1 pressure ulcer K1 sevoflurane K1 topical treatment AB Recently, it has been reported that topical irrigations of liquid sevoflurane on the bed of painful wounds produce a rapid, intense, and lasting analgesic effect. In this paper, A cohort of 112 patients with painful pressure ulcers who were refractory to opioids (or who exhibited undesirable adverse events to them) was treated with topical sevoflurane as per local institutional policy. These patients were recruited from an intensive care unit for a period of 3 years. The main aim was to determine the effectiveness of topical sevoflurane in reducing the pain of PUs and reducing the ulcer area. Study findings are reported and discussed herein and suggest that sevoflurane is a viable and promising treatment option for PUs. YR 2019 FD 2019-11-25 LK http://hdl.handle.net/10668/14738 UL http://hdl.handle.net/10668/14738 LA en DS RISalud RD Apr 19, 2025