Publication: The Presence of Precursors of Benign Pre-B Lymphoblasts (Hematogones) in the Bone Marrow of a Paediatric Patient with Cytomegalovirus Infection
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Identifiers
Date
2008-05-20
Authors
Moreno-Madrid, F
Uberos, J
Díaz-Molina, M
Ramírez-Arredondo, A
Jiménez-Gámiz, P
Molina-Carballo, A
Advisors
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Publisher
Libertas Academica
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Abstract
Hematogones are normal B-lymphoid precursors that multiply in the bone marrow of small children and of adults with ferropenic anaemia, neuroblastoma or idiopathic thrombocytopenic purpura. They are not normally found in peripheral blood, and the immunophenotype is virtually indistinguishable from that of B lymphoblasts. We discuss the case of a
3-month infant with an active cytomegalovirus infection, with hepatitis and pancytopenia associated with 13% hematogones in the bone marrow
Description
Case report
MeSH Terms
Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::B-Lymphocytes::Precursor Cells, B-Lymphoid
Medical Subject Headings::Organisms::Viruses::DNA Viruses::Herpesviridae::Betaherpesvirinae::Cytomegalovirus
Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Leukemia::Leukemia, Lymphoid::Precursor Cell Lymphoblastic Leukemia-Lymphoma
Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Leukemia
Medical Subject Headings::Named Groups::Persons::Age Groups::Infant
Medical Subject Headings::Organisms::Viruses::DNA Viruses::Herpesviridae::Betaherpesvirinae::Cytomegalovirus
Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Leukemia::Leukemia, Lymphoid::Precursor Cell Lymphoblastic Leukemia-Lymphoma
Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Leukemia
Medical Subject Headings::Named Groups::Persons::Age Groups::Infant
DeCS Terms
CIE Terms
Keywords
Células Precursoras de Linfocitos B, Citomegalovirus, Lactante, Leucemia, Leucemia-Linfoma Linfoblástico de Células Precursoras, Hematogones, Pre-B cells, Cytomegalovirus, Infants, Leukemia, Acute lymphoblastic leukemia
Citation
Moreno-Madrid F, Uberos J, Díaz-Molina M, Ramírez-Arredondo A, Jiménez-Gámiz P, Molina-Carballo A.The Presence of Precursors of Benign Pre-B Lymphoblasts (Hematogones) in the Bone Marrow of a Paediatric Patient with Cytomegalovirus Infection.Clin Med Oncol. 2008;2:437-9