Publication: Assessment of the EarlyCDT-Lung test as an early biomarker of lung cancer in ever-smokers: A retrospective nested case-control study in two prospective cohorts.
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Identifiers
Date
2022-10-05
Authors
Wu, Wendy Yi-Ying
Haider, Zahra
Feng, Xiaoshuang
Heath, Alicia K
Tjønneland, Anne
Agudo, Antonio
Masala, Giovanna
Robbins, Hilary A
Huerta, Jose-Maria
Guevara, Marcela
Advisors
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Journal ISSN
Volume Title
Publisher
John Wiley & Sons, Inc.
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Abstract
The EarlyCDT-Lung test is a blood-based autoantibody assay intended to identify high-risk individuals for low-dose computed tomography lung cancer screening. However, there is a paucity of evidence on the performance of the EarlyCDT-Lung test in ever-smokers. We conducted a nested case-control study within two prospective cohorts to evaluate the risk-discriminatory performance of the EarlyCDT-Lung test using prediagnostic blood samples from 154 future lung cancer cases and 154 matched controls. Cases were selected from those who had ever smoked and had a prediagnostic blood sample
Description
MeSH Terms
Humans
Lung Neoplasms
Case-Control Studies
Retrospective Studies
Early Detection of Cancer
Smokers
Prospective Studies
Biomarkers
Lung
Lung Neoplasms
Case-Control Studies
Retrospective Studies
Early Detection of Cancer
Smokers
Prospective Studies
Biomarkers
Lung
DeCS Terms
Biomarcadores
Detección precoz del cáncer
Estudios prospectivos
Estudios retrospectivos
Estudios de casos y controles
Fumadores
Humanos
Neoplasias pulmonares
Pulmón
Detección precoz del cáncer
Estudios prospectivos
Estudios retrospectivos
Estudios de casos y controles
Fumadores
Humanos
Neoplasias pulmonares
Pulmón
CIE Terms
Keywords
EarlyCDT-Lung test, biomarkers, lung cancer, prediagnostic samples
Citation
Wu WY, Haider Z, Feng X, Heath AK, Tjønneland A, Agudo A, et al. Assessment of the EarlyCDT-Lung test as an early biomarker of lung cancer in ever-smokers: A retrospective nested case-control study in two prospective cohorts. Int J Cancer. 2023 May 1;152(9):2002-2010.