Publication:
Restless Leg Syndrome in Peripheral Artery Disease: Prevalence among Patients with Claudication and Benefits from Low-Intensity Exercise.

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Date

2019-09-04

Authors

Lamberti, Nicola
Lopez-Soto, Pablo Jesus
Rodriguez-Borrego, Maria Aurora
Straudi, Sofia
Basaglia, Nino
Zamboni, Paolo
Manfredini, Roberto
Manfredini, Fabio

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MDPI
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Abstract

Restless leg syndrome (RLS) disrupts sleep, affecting the quality of life of patients with various chronic diseases. We assessed the prevalence of RLS in peripheral artery disease (PAD) patients and the effects of a pain-free exercise program. A total of 286 patients with claudication were enrolled in a home-based low-intensity exercise program prescribed at the hospital. RLS was determined through standardized questions. Hemodynamics, degree of calf deoxygenation, and mobility were assessed using the ankle-brachial-index, a treadmill test assisted by near-infrared spectroscopy and the 6-min walk test, respectively. During hospital visits, persistence of RLS, adherence to exercise, hemodynamics, and mobility were assessed. At the enrollment, 101 patients (35%) presented RLS, with higher prevalence among females (p = 0.032). Compared to RLS-free patients, they showed similar hemodynamics but more severe calf deoxygenation (p

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MeSH Terms

Rehabilitation
Restless leg syndrome
Spectroscopy

DeCS Terms

Análisis espectral
Rehabilitación
Síndrome de las piernas inquietas

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Keywords

Exercise therapy, Near-infrared, Peripheral artery disease

Citation

Lamberti N, López-Soto PJ, Rodríguez-Borrego MA, Straudi S, Basaglia N, Zamboni P, et al. Restless Leg Syndrome in Peripheral Artery Disease: Prevalence among Patients with Claudication and Benefits from Low-Intensity Exercise. J Clin Med. 2019 Sep 6;8(9):1403