RT Journal Article T1 Restless Leg Syndrome in Peripheral Artery Disease: Prevalence among Patients with Claudication and Benefits from Low-Intensity Exercise. A1 Lamberti, Nicola A1 Lopez-Soto, Pablo Jesus A1 Rodriguez-Borrego, Maria Aurora A1 Straudi, Sofia A1 Basaglia, Nino A1 Zamboni, Paolo A1 Manfredini, Roberto A1 Manfredini, Fabio K1 Exercise therapy K1 Near-infrared K1 Peripheral artery disease AB Restless leg syndrome (RLS) disrupts sleep, affecting the quality of life of patients with various chronic diseases. We assessed the prevalence of RLS in peripheral artery disease (PAD) patients and the effects of a pain-free exercise program. A total of 286 patients with claudication were enrolled in a home-based low-intensity exercise program prescribed at the hospital. RLS was determined through standardized questions. Hemodynamics, degree of calf deoxygenation, and mobility were assessed using the ankle-brachial-index, a treadmill test assisted by near-infrared spectroscopy and the 6-min walk test, respectively. During hospital visits, persistence of RLS, adherence to exercise, hemodynamics, and mobility were assessed. At the enrollment, 101 patients (35%) presented RLS, with higher prevalence among females (p = 0.032). Compared to RLS-free patients, they showed similar hemodynamics but more severe calf deoxygenation (p PB MDPI SN 2077-0383 YR 2019 FD 2019-09-04 LK http://hdl.handle.net/10668/14485 UL http://hdl.handle.net/10668/14485 LA en NO Lamberti N, López-Soto PJ, Rodríguez-Borrego MA, Straudi S, Basaglia N, Zamboni P, et al. Restless Leg Syndrome in Peripheral Artery Disease: Prevalence among Patients with Claudication and Benefits from Low-Intensity Exercise. J Clin Med. 2019 Sep 6;8(9):1403 DS RISalud RD Apr 11, 2025