Publication:
Increased Expression of Musashi-1 Evidences Mesenchymal Repair in Maxillary Sinus Floor Elevation.

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dc.contributor.authorO'Valle, Francisco
dc.contributor.authorde Buitrago, Juan G
dc.contributor.authorHernández-Cortés, Pedro
dc.contributor.authorPadial-Molina, Miguel
dc.contributor.authorCrespo-Lora, Vicente
dc.contributor.authorCobo, Marien
dc.contributor.authorAguilar, David
dc.contributor.authorGalindo-Moreno, Pablo
dc.date.accessioned2023-01-25T10:21:29Z
dc.date.available2023-01-25T10:21:29Z
dc.date.issued2018-08-16
dc.description.abstractThis study aimed to analyze the expression of Musashi-1 (MSI1) in maxillary native bone and grafted bone after maxillary sinus floor elevation. To do so, fifty-seven bone biopsies from 45 participants were studied. Eighteen samples were collected from native bone while 39 were obtained 6 months after maxillary sinus grafting procedures. Musashi-1 was analyzed by immunohistochemistry and RT-PCR. MSI1 was detected in osteoblasts and osteocytes in 97.4% (38/39) of grafted areas. In native bone, MSI1 was detected in only 66.6% (12/18) of the biopsies, mainly in osteocytes. Detection of MSI1 was significantly higher in osteoprogenitor mesenchymal cells of grafted biopsies (p 
dc.identifier.doi10.1038/s41598-018-29908-3
dc.identifier.essn2045-2322
dc.identifier.pmcPMC6095840
dc.identifier.pmid30116022
dc.identifier.pubmedURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095840/pdf
dc.identifier.unpaywallURLhttps://www.nature.com/articles/s41598-018-29908-3.pdf
dc.identifier.urihttp://hdl.handle.net/10668/12845
dc.issue.number1
dc.journal.titleScientific reports
dc.journal.titleabbreviationSci Rep
dc.language.isoen
dc.organizationHospital Universitario San Cecilio
dc.organizationCentro Pfizer-Universidad de Granada-Junta de Andalucía de Genómica e Investigación Oncológica-GENYO
dc.organizationHospital Universitario San Cecilio
dc.page.number12243
dc.pubmedtypeJournal Article
dc.pubmedtypeResearch Support, Non-U.S. Gov't
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshBiopsy
dc.subject.meshCell Differentiation
dc.subject.meshFemale
dc.subject.meshGene Expression Regulation
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMaxillary Sinus
dc.subject.meshMesenchymal Stem Cells
dc.subject.meshMiddle Aged
dc.subject.meshNerve Tissue Proteins
dc.subject.meshOsteoblasts
dc.subject.meshOsteocytes
dc.subject.meshRNA, Messenger
dc.subject.meshRNA-Binding Proteins
dc.subject.meshSinus Floor Augmentation
dc.titleIncreased Expression of Musashi-1 Evidences Mesenchymal Repair in Maxillary Sinus Floor Elevation.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number8
dspace.entity.typePublication

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