The Emerging Role of RNA Modifications in DNA Double-Strand Break Repair

Jimeno, Sonia; Balestra, Fernando R.; Huertas, Pablo

Publication:
The Emerging Role of RNA Modifications in DNA Double-Strand Break Repair

dc.contributor.author	Jimeno, Sonia
dc.contributor.author	Balestra, Fernando R.
dc.contributor.author	Huertas, Pablo
dc.contributor.authoraffiliation	[Jimeno,S; Balestra,FR; Huertas,P] Departamento de Genética, Universidad de Sevilla, Seville, Spain. [Jimeno,S; Balestra,FR; Huertas,P] Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, Seville, Spain.
dc.contributor.funder	This work was funded by the R+D+I grant PID2019-104195G from the Spanish Ministry of Science and Innovation-Agencia Estatal de Investigación/10.13039/501100011033. FB is funded by the University of Seville through a postdoctoral contract of the V PPIT-US. CABIMER is supported by the Regional Government of Andalucia (Junta de Andalucía).
dc.date.accessioned	2022-10-07T10:14:02Z
dc.date.available	2022-10-07T10:14:02Z
dc.date.issued	2021-04-29
dc.description.abstract	The correct repair of DNA double-strand breaks is essential for maintaining the stability of the genome, thus ensuring the survival and fitness of any living organism. Indeed, the repair of these lesions is a complicated affair, in which several pathways compete for the DNA ends in a complex balance. Thus, the fine-tuning of the DNA double-strand break repair pathway choice relies on the different regulatory layers that respond to environmental cues. Among those different tiers of regulation, RNA modifications have just emerged as a promising field.	es_ES
dc.description.version	Yes	es_ES
dc.identifier.citation	Jimeno S, Balestra FR, Huertas P. The Emerging Role of RNA Modifications in DNA Double-Strand Break Repair. Front Mol Biosci. 2021 Apr 29;8:664872	es_ES
dc.identifier.doi	10.3389/fmolb.2021.664872	es_ES
dc.identifier.essn	2296-889X
dc.identifier.pmc	PMC8116738
dc.identifier.pmid	33996910	es_ES
dc.identifier.uri	http://hdl.handle.net/10668/4246
dc.journal.title	Frontiers in Molecular Biosciences
dc.language.iso	en
dc.page.number	10 p.
dc.publisher	Frontiers	es_ES
dc.relation.publisherversion	https://www.frontiersin.org/articles/10.3389/fmolb.2021.664872/full	es_ES
dc.rights	Atribución 4.0 Internacional	*
dc.rights.accessRights	Acceso abierto	es_ES
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/	*
dc.subject	RNA modification	es_ES
dc.subject	DNA repair	es_ES
dc.subject	Homologous recombination	es_ES
dc.subject	DNA resection	es_ES
dc.subject	R-loop	es_ES
dc.subject	Procesamiento postranscripcional del ARN	es_ES
dc.subject	Reparación del ADN	es_ES
dc.subject	Recombinación homóloga	es_ES
dc.subject	Estructuras R-loop	es_ES
dc.subject	ADN	es_ES
dc.subject.mesh	Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Damage::DNA Breaks::DNA Breaks, Double-Stranded	es_ES
dc.subject.mesh	Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA::DNA, Single-Stranded	es_ES
dc.subject.mesh	Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Base Sequence	es_ES
dc.subject.mesh	Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Recombination, Genetic::Homologous Recombination	es_ES
dc.subject.mesh	Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Sequence Homology	es_ES
dc.subject.mesh	Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Nucleoproteins	es_ES
dc.subject.mesh	Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Genetics::Genomics	es_ES
dc.subject.mesh	Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Repair	es_ES
dc.subject.mesh	Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome	es_ES
dc.title	The Emerging Role of RNA Modifications in DNA Double-Strand Break Repair	es_ES
dc.type	review article
dc.type.hasVersion	VoR
dspace.entity.type	Publication