Publication:
Impact of the PROVAUR stewardship programme on linezolid resistance in a tertiary university hospital: a before-and-after interventional study.

Simple item page
dc.contributor.authorGarcia-Martinez, Lucrecia
dc.contributor.authorGracia-Ahulfinger, Irene
dc.contributor.authorMachuca, Isabel
dc.contributor.authorCantisan, Sara
dc.contributor.authorDe La Fuente, Soraya
dc.contributor.authorNatera, Clara
dc.contributor.authorPerez-Nadales, Elena
dc.contributor.authorVidal, Elisa
dc.contributor.authorRivero, Antonio
dc.contributor.authorRodriguez-Lopez, Fernando
dc.contributor.authorDel Prado, Jose Ramon
dc.contributor.authorTorre-Cisneros, Julian
dc.contributor.funderInstituto de Salud Carlos III
dc.contributor.funderSubdirección General de Redes y Centros de Investigación Cooperativa,
dc.contributor.funderMinisterio de Economıía y Competitividad
dc.contributor.funderSpanish Network for Research in Infectious Diseases [Red Española de Investigación de Patología Infecciosa
dc.contributor.funderEuropean Development Regional Fund (ERDF) ‘A way to achieve Europe’
dc.date.accessioned2023-01-25T08:33:03Z
dc.date.available2023-01-25T08:33:03Z
dc.date.issued2016-04-20
dc.description.abstractThere is little evidence of the impact of antimicrobial stewardship programmes on antimicrobial resistance. To study the efficacy and safety of a package of educational and interventional measures to optimize linezolid use and its impact on bacterial resistance. A quasi-experimental study was designed and carried out before and after implementation of a stewardship programme in hospitalized patients with Gram-positive infections treated with linezolid. The intervention reduced linezolid consumption by 76%. The risk of linezolid-resistant CoNS isolates (OR = 0.37; 95% CI = 0.27-0.49; P  A programme to optimize linezolid use can contribute to reducing the resistance rate of CoNS and E. faecalis to this antibiotic.
dc.description.versionSi
dc.identifier.citationGarcía-Martínez L, Gracia-Ahulfinger I, Machuca I, Cantisán S, De La Fuente S, Natera C, et al. Impact of the PROVAUR stewardship programme on linezolid resistance in a tertiary university hospital: a before-and-after interventional study. J Antimicrob Chemother. 2016 Sep;71(9):2606-11
dc.identifier.doi10.1093/jac/dkw179
dc.identifier.essn1460-2091
dc.identifier.pmid27246230
dc.identifier.unpaywallURLhttps://academic.oup.com/jac/article-pdf/71/9/2606/17430221/dkw179.pdf
dc.identifier.urihttp://hdl.handle.net/10668/10140
dc.issue.number9
dc.journal.titleThe Journal of antimicrobial chemotherapy
dc.journal.titleabbreviationJ Antimicrob Chemother
dc.language.isoen
dc.organizationHospital Universitario Reina Sofía
dc.organizationInstituto Maimónides de Investigación Biomédica de Córdoba-IMIBIC
dc.page.number2606-11
dc.provenanceRealizada la curación de contenido 21/08/2024
dc.publisherOxford University Press
dc.pubmedtypeJournal Article
dc.pubmedtypeResearch Support, Non-U.S. Gov't
dc.relation.projectIDRD06/0008
dc.relation.projectIDRD12/0015
dc.relation.publisherversionhttps://academic.oup.com/jac/article/71/9/2606/2238187?login=false
dc.rights.accessRightsopen access
dc.subjectAnti-bacterial agents
dc.subjectAttitude of health personnel
dc.subjectBehavior therapy
dc.subjectDrug resistance, bacterial
dc.subject.decsCentros de atención terciaria
dc.subject.decsEducación médica continua
dc.subject.decsEstudios retrospectivos
dc.subject.decsHospitales universitarios
dc.subject.decsInfecciones por bacterias grampositivas
dc.subject.decsPolítica de salud
dc.subject.decsUtilización de medicamentos
dc.subject.meshDrug utilization
dc.subject.meshEducation, medical, continuing
dc.subject.meshEnterococcus faecalis
dc.subject.meshGram-positive bacterial infections
dc.subject.meshHealth policy
dc.subject.meshHospitals, university
dc.subject.meshHumans
dc.subject.meshLinezolid
dc.subject.meshNon-randomized controlled trials as topic
dc.subject.meshRetrospective studies
dc.subject.meshStaphylococcus
dc.subject.meshSurveys and questionnaires
dc.subject.meshTertiary care centers
dc.titleImpact of the PROVAUR stewardship programme on linezolid resistance in a tertiary university hospital: a before-and-after interventional study.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number71
dspace.entity.typePublication

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
RISalud_Accesorestringido.pdf
Size:
93.39 KB
Format:
Adobe Portable Document Format
Download

Collections

SAS - Hospital Universitario Reina Sofía
Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC)

© 2023 – Repositorio Institucional de Salud de Andalucía - Fundación Pública Andaluza Progreso y Salud - Consejería de Salud y Consumo de la Junta de Andalucía