Publication:
Prosthetic Mitral Surgical Valve in Transcatheter Aortic Valve Replacement Recipients: A Multicenter Analysis.

No Thumbnail Available

Date

2017

Authors

Amat-Santos, Ignacio J
Cortés, Carlos
Nombela Franco, Luis
Muñoz-García, Antonio J
Suárez De Lezo, Jose
Gutiérrez-Ibañes, Enrique
Serra, Vicenç
Larman, Mariano
Moreno, Raúl
De La Torre Hernandez, Jose M

Advisors

Journal Title

Journal ISSN

Volume Title

Publisher

Metrics
Google Scholar
Export

Research Projects

Organizational Units

Journal Issue

Abstract

The aim of this study was to determine the prognosis and specific complications of patients with prosthetic mitral valves (PMVs) undergoing transcatheter aortic valve replacement (TAVR). TAVR is performed relatively often in patients with PMVs, but specific risks are not well described. A multicenter analysis was conducted, including patients with severe symptomatic aortic stenosis who underwent TAVR at 10 centers. Patients' clinical characteristics and outcomes were evaluated according to the presence of a PMV. The mean age of the study population (n = 2,414) was 81 ± 8 years, and 48.8% were men. A total of 91 patients (3.77%) had PMVs. They were more commonly women, younger, and had higher surgical risk. PMVs were implanted a median of 14 years before TAVR, and most patients had mechanical prostheses (73.6%). Eighty-six patients (94.5%) were on long-term vitamin K inhibitor therapy, and bridging antithrombotic therapy was administered in 59 (64.8%). TAVR device embolization occurred in 6.7% (vs. 3.3% in the non-PMV group; p = 0.127), in all instances when distance between the PMV and the aortic annulus was  TAVR presents similar mortality irrespective of the presence of a PMV. However, patients with PMVs had higher bleeding risk that was independently associated with higher mortality. Risk for valve embolization was relatively high, but it occurred only in patients with PMV-to-aortic annulus distances 

Description

MeSH Terms

Aged
Aged, 80 and over
Aortic Valve
Aortic Valve Stenosis
Female
Heart Valve Prosthesis
Heart Valve Prosthesis Implantation
Humans
Male
Mitral Valve
Postoperative Complications
Prosthesis Design
Registries
Retrospective Studies
Risk Factors
Severity of Illness Index
Time Factors
Transcatheter Aortic Valve Replacement
Treatment Outcome

DeCS Terms

CIE Terms

Keywords

TAVR, mitral prostheses, multivalvular disease

Citation