RT Journal Article
T1 Prosthetic Mitral Surgical Valve in Transcatheter Aortic Valve Replacement Recipients: A Multicenter Analysis.
A1 Amat-Santos, Ignacio J
A1 Cortés, Carlos
A1 Nombela Franco, Luis
A1 Muñoz-García, Antonio J
A1 Suárez De Lezo, Jose
A1 Gutiérrez-Ibañes, Enrique
A1 Serra, Vicenç
A1 Larman, Mariano
A1 Moreno, Raúl
A1 De La Torre Hernandez, Jose M
A1 Puri, Rishi
A1 Jimenez-Quevedo, Pilar
A1 Hernández García, José M
A1 Alonso-Briales, Juan H
A1 García, Bruno
A1 Lee, Dae-Hyun
A1 Rojas, Paol
A1 Sevilla, Teresa
A1 Goncalves, Renier
A1 Vera, Silvio
A1 Gómez, Itziar
A1 Rodés-Cabau, Josep
A1 San Román, José A
K1 TAVR
K1 mitral prostheses
K1 multivalvular disease
AB The aim of this study was to determine the prognosis and specific complications of patients with prosthetic mitral valves (PMVs) undergoing transcatheter aortic valve replacement (TAVR). TAVR is performed relatively often in patients with PMVs, but specific risks are not well described. A multicenter analysis was conducted, including patients with severe symptomatic aortic stenosis who underwent TAVR at 10 centers. Patients' clinical characteristics and outcomes were evaluated according to the presence of a PMV. The mean age of the study population (n = 2,414) was 81 ± 8 years, and 48.8% were men. A total of 91 patients (3.77%) had PMVs. They were more commonly women, younger, and had higher surgical risk. PMVs were implanted a median of 14 years before TAVR, and most patients had mechanical prostheses (73.6%). Eighty-six patients (94.5%) were on long-term vitamin K inhibitor therapy, and bridging antithrombotic therapy was administered in 59 (64.8%). TAVR device embolization occurred in 6.7% (vs. 3.3% in the non-PMV group; p = 0.127), in all instances when distance between the PMV and the aortic annulus was  TAVR presents similar mortality irrespective of the presence of a PMV. However, patients with PMVs had higher bleeding risk that was independently associated with higher mortality. Risk for valve embolization was relatively high, but it occurred only in patients with PMV-to-aortic annulus distances 
YR 2017
FD 2017
LK http://hdl.handle.net/10668/11652
UL http://hdl.handle.net/10668/11652
LA en
DS RISalud
RD Apr 10, 2025