Publication: Long-term effects of varying consumption of ω3 fatty acids in ear, nose and throat cancer patients: assessment 1 year after radiotherapy.
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Identifiers
Date
2015-02
Authors
Roca-Rodríguez, María del Mar
García-Almeida, José Manuel
Ruiz-Nava, Josefina
Alcaide, Juan
Lupiáñez-Pérez, Yolanda
Rico-Pérez, José Manuel
Toledo-Serrano, María Dolores
Cardona, Fernando
Medina-Carmona, José Antonio
Tinahones, Francisco J
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
Informa Healthcare
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Abstract
Abstract A prospective 1-year follow-up study in ear, nose, and throat (ENT) cancer patients was carried out one year after radiotherapy to assess the effect of varying consumption of ω3 fatty acid according to whether they consumed more or less than the 50th percentile of ω3 fatty acids. Clinical, analytical, inflammatory (CRP and IL-6), and oxidative variables (TAC, GPx, GST, and SOD) were evaluated. The study comprised 31 patients (87.1% men), with a mean age of 61.3 ± 9.1 years. Hematological variables showed significant differences in the patients with a lower consumption of ω3 fatty acids. A lower mortality and longer survival were found in the group with ω3 fatty acid consumption ≥50th percentile but the differences were not significant. No significant difference was reached in toxicity, inflammation, and oxidative stress markers. The group with ω3 fatty acid consumption <50th percentile significantly experienced more hematological and immune changes.
Description
Journal Article;
MeSH Terms
Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Antioxidants
Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers
Medical Subject Headings::Health Care::Environment and Public Health::Public Health::Epidemiologic Measurements::Biometry::Anthropometry::Body Mass Index
Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Albumins::C-Reactive Protein
Medical Subject Headings::Technology, Industry, Agriculture::Food and Beverages::Food::Dietary Fiber
Medical Subject Headings::Technology, Industry, Agriculture::Food and Beverages::Food::Dietary Supplements
Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Head and Neck Neoplasms::Otorhinolaryngologic Neoplasms::Ear Neoplasms
Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Electrolytes
Medical Subject Headings::Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids, Unsaturated
Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Peroxidases::Glutathione Peroxidase
Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Electrolytes::Ions::Anions::Oxides::Peroxides::Hydrogen Peroxide
Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Inflammation
Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines::Interleukins::Interleukin-6
Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Malnutrition
Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Head and Neck Neoplasms::Otorhinolaryngologic Neoplasms::Nose Neoplasms
Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Oxidative Stress
Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Head and Neck Neoplasms::Otorhinolaryngologic Neoplasms::Pharyngeal Neoplasms
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers
Medical Subject Headings::Health Care::Environment and Public Health::Public Health::Epidemiologic Measurements::Biometry::Anthropometry::Body Mass Index
Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Albumins::C-Reactive Protein
Medical Subject Headings::Technology, Industry, Agriculture::Food and Beverages::Food::Dietary Fiber
Medical Subject Headings::Technology, Industry, Agriculture::Food and Beverages::Food::Dietary Supplements
Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Head and Neck Neoplasms::Otorhinolaryngologic Neoplasms::Ear Neoplasms
Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Electrolytes
Medical Subject Headings::Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids, Unsaturated
Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Peroxidases::Glutathione Peroxidase
Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Electrolytes::Ions::Anions::Oxides::Peroxides::Hydrogen Peroxide
Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Inflammation
Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines::Interleukins::Interleukin-6
Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Malnutrition
Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Head and Neck Neoplasms::Otorhinolaryngologic Neoplasms::Nose Neoplasms
Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Oxidative Stress
Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Head and Neck Neoplasms::Otorhinolaryngologic Neoplasms::Pharyngeal Neoplasms
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
DeCS Terms
CIE Terms
Keywords
Nutritional supplement, Cancer, Clinical study, Metabolic status, Survival, Antioxidantes, Marcadores biológicos, Índice de masa corporal, Proteina C reactiva, Suplementos dietéticos, Cáncer de oído, Electrolitos, Ácidos grasos insaturados, Glutatión peroxidasa, Peróxido de hidrógeno, Inflamación, Interleucina-6, Desnutrición, Neoplasias nasales, Estres oxidativo, Neoplasias faríngeas
Citation
Roca-Rodríguez M del M, García-Almeida JM, Ruiz-Nava J, Alcaide J, Lupiañez-Pérez Y, Rico-Pérez JM, et al. Long-term effects of varying consumption of ω3 fatty acids in ear, nose and throat cancer patients: assessment 1 year after radiotherapy. Int J Food Sci Nutr. 2015; 66(1):108-13