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Amplification-free profiling of microRNA-122 biomarker in DILI patient serums, using the luminex MAGPIX system.

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dc.contributor.authorMarín-Romero, Antonio
dc.contributor.authorTabraue-Chávez, Mavys
dc.contributor.authorDear, James W
dc.contributor.authorSánchez-Martín, Rosario M
dc.contributor.authorIlyine, Hugh
dc.contributor.authorGuardia-Monteagudo, Juan J
dc.contributor.authorFara, Mario A
dc.contributor.authorLópez-Delgado, Francisco J
dc.contributor.authorDíaz-Mochón, Juan J
dc.contributor.authorPernagallo, Salvatore
dc.date.accessioned2023-02-09T09:39:55Z
dc.date.available2023-02-09T09:39:55Z
dc.date.issued2020-06-29
dc.description.abstractDynamic chemical labelling is a single-base specific method to enable detection and quantification of micro-Ribonucleic Acids in biological fluids without extraction and pre-amplification. In this study, dynamic chemical labelling was combined with the Luminex MAGPIX system to profile levels of microRNA-122 biomarker in serum from patients with Drug-Induced Liver Injury.
dc.identifier.doi10.1016/j.talanta.2020.121265
dc.identifier.essn1873-3573
dc.identifier.pmid32887156
dc.identifier.unpaywallURLhttp://hdl.handle.net/20.500.11820/0a858c85-7069-4074-ac0b-445184f15c78
dc.identifier.urihttp://hdl.handle.net/10668/16205
dc.journal.titleTalanta
dc.journal.titleabbreviationTalanta
dc.language.isoen
dc.organizationCentro Pfizer-Universidad de Granada-Junta de Andalucía de Genómica e Investigación Oncológica-GENYO
dc.page.number121265
dc.pubmedtypeJournal Article
dc.rights.accessRightsopen access
dc.subjectDrug-induced liver injury (DILI)
dc.subjectDynamic chemical labelling (DCL)
dc.subjectLiquid biopsy
dc.subjectLuminex MAGPIX
dc.subjectmiRNA-122
dc.subject.meshBiomarkers
dc.subject.meshChemical and Drug Induced Liver Injury
dc.subject.meshHumans
dc.subject.meshMicroRNAs
dc.titleAmplification-free profiling of microRNA-122 biomarker in DILI patient serums, using the luminex MAGPIX system.
dc.typeresearch article
dc.type.hasVersionSMUR
dc.volume.number219
dspace.entity.typePublication

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